Literature DB >> 29093405

Mycotic Aneurysm Mimicking Atheroma in Aortic Arch.

Yueh-An Lu1,2,3, Wen-Hung Huang1,2,3, Tzung-Hai Yen1,2,3, Ching-Wei Hsu1,2,3.   

Abstract

Entities:  

Keywords:  atherosclerosis; mycotic aneurysm

Year:  2017        PMID: 29093405      PMCID: PMC5820057          DOI: 10.2169/internalmedicine.9214-17

Source DB:  PubMed          Journal:  Intern Med        ISSN: 0918-2918            Impact factor:   1.271


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A 51-year-old hemodialysis patient was admitted for methicillin-sensitive Staphylococcus aureus (MSSA) bacteremia from an unknown primary focus. A transthoracic echocardiogram showed no cardiac vegetation. 18F-fludeoxyglucose positron emission tomography (18F-FDG PET) revealed an increased uptake in the aortic arch (Picture 1, white arrow) with a maximum standard uptake value of 5.30. Both atherosclerosis and inflammation were considered. The patient completed 4 weeks of effective antibiotic treatment, but recurrent MSSA bacteremia developed again 2 months later. Transesophageal echocardiography to rule out infective endocarditis revealed no vegetation, but a pseudoaneurysm was identified at the aortic arch. Computed tomography angiography (CTA) was done 2 months after the PET study and disclosed the presence of a 3.4 cm aortic aneurysm with periaortic fluid, which was compatible with a mycotic aneurysm (Picture 2, white arrow). A mycotic aneurysm in the aortic arch is a rare, but life-threatening development (1). 18F-FDG PET is sensitive and reproducible for delineating vascular inflammation (e.g., vasculitis and atherosclerosis) (2), and it can also detect infected aortic aneurysms. It may be useful to identify the presence of a mycotic aneurysm in the aortic arch, especially in hemodialysis patients.
Picture 1.
Picture 2.
The authors state that they have no Conflict of Interest (COI).
  2 in total

1.  Rapidly progressing aneurysm of infected thoracic aorta with pseudoaneurysm formation.

Authors:  Akio Iimori; Yumiko Kanzaki; Shinpei Ito; Takuya Kotani; Suzue Hirano-Kuwata; Masahiro Daimon; Takahiro Katsumata; Hiroyuki Akagi; Tsuyoshi Komori; Fumio Terasaki; Nobukazu Ishizaka; Akira Ukimura
Journal:  Intern Med       Date:  2010-11-15       Impact factor: 1.271

Review 2.  Molecular imaging of atherosclerosis with integrated PET imaging.

Authors:  Basma Hammad; Nicholas R Evans; James H F Rudd; Ahmed Tawakol
Journal:  J Nucl Cardiol       Date:  2017-01-11       Impact factor: 5.952

  2 in total

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