| Literature DB >> 29092642 |
Miao Yang1, Yan Zhang2, Lijun Chen2, Yegao Chen1.
Abstract
A new (propylphenyl)bibenzyl derivative, dendrowillol A (1), along with 22 known compounds were isolated from the whole plants of Dendrobium williamsonii. Their structures were elucidated by means of extensive spectroscopic analysis. Cytotoxicity evaluation against five human tumour lines showed that all the compounds tested displayed very weak cytotoxicity when compared with the positive control taxol, but selective inhibitory effects on HL-60 for several compounds tested were observed, with IC50 values ranging from 4.48 to 11.04 μM.Entities:
Keywords: Dendrobium williamsonii; Orchidaceae; dendrowillol A
Mesh：
Substances：
Year: 2017 PMID： 29092642 DOI： 10.1080/14786419.2017.1396599
Source DB: PubMed Journal: Nat Prod Res ISSN： 1478-6419 Impact factor: 2.861