Literature DB >> 29092508

Development of a combined OCT-Raman probe for the prospective in vivo clinical melanoma skin cancer screening.

M Mazurenka1, L Behrendt1, M Meinhardt-Wollweber1, U Morgner2, B Roth1.   

Abstract

A combined optical coherence tomography (OCT)-Raman probe was designed and built into a spectral domain OCT head, and its performance was evaluated and compared to the most common Raman probe setups, based on a fiber bundle and confocal free space optics. Due to the use of the full field of view of an OCT scanning lens, the combined probe has a superior performance within maximum permissible exposure limits, compared to the other two probes. Skin Raman spectra, recorded in vivo, further prove the feasibility of the OCT-Raman probe for the future in vivo clinical applications in skin cancer screening.

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Year:  2017        PMID： 29092508     DOI： 10.1063/1.5004999

Source DB:  PubMed          Journal:  Rev Sci Instrum        ISSN： 0034-6748            Impact factor:   1.523


  5 in total

Review 1.  Raman Sensing and Its Multimodal Combination with Optoacoustics and OCT for Applications in the Life Sciences.

Authors:  Merve Wollweber; Bernhard Roth
Journal:  Sensors (Basel)       Date:  2019-05-24       Impact factor: 3.576

2.  Optical coherence tomography-guided confocal Raman microspectroscopy for rapid measurements in tissues.

Authors:  Xiaojing Ren; Kan Lin; Chao-Mao Hsieh; Linbo Liu; Xin Ge; Quan Liu
Journal:  Biomed Opt Express       Date:  2021-12-14       Impact factor: 3.732

3.  Multimodal Approach of Optical Coherence Tomography and Raman Spectroscopy Can Improve Differentiating Benign and Malignant Skin Tumors in Animal Patients.

Authors:  Mindaugas Tamošiūnas; Oskars Čiževskis; Daira Viškere; Mikus Melderis; Uldis Rubins; Blaž Cugmas
Journal:  Cancers (Basel)       Date:  2022-06-07       Impact factor: 6.575

4.  Co-localized line-field confocal optical coherence tomography and confocal Raman microspectroscopy for three-dimensional high-resolution morphological and molecular characterization of skin tissues ex vivo.

Authors:  Léna Waszczuk; Jonas Ogien; Jean-Luc Perrot; Arnaud Dubois
Journal:  Biomed Opt Express       Date:  2022-03-25       Impact factor: 3.562

5.  Morpho-molecular signal correlation between optical coherence tomography and Raman spectroscopy for superior image interpretation and clinical diagnosis.

Authors:  Iwan W Schie; Fabian Placzek; Florian Knorr; Eliana Cordero; Lara M Wurster; Gregers G Hermann; Karin Mogensen; Thomas Hasselager; Wolfgang Drexler; Jürgen Popp; Rainer A Leitgeb
Journal:  Sci Rep       Date:  2021-05-11       Impact factor: 4.379
  5 in total

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