Literature DB >> 29091066

Characterization of a sCMOS-based high-resolution imaging system.

Alberto Mittone1, Ilja Manakov2, Ludovic Broche3, Christophe Jarnias1, Paola Coan2, Alberto Bravin1.   

Abstract

The detection system is a key part of any imaging station. Here the performance of the novel sCMOS-based detection system installed at the ID17 biomedical beamline of the European Synchrotron Radiation Facility and dedicated to high-resolution computed-tomography imaging is analysed. The system consists of an X-ray-visible-light converter, a visible-light optics and a PCO.Edge5.5 sCMOS detector. Measurements of the optical characteristics, the linearity of the system, the detection lag, the modulation transfer function, the normalized power spectrum, the detective quantum efficiency and the photon transfer curve are presented and discussed. The study was carried out at two different X-ray energies (35 and 50 keV) using both 2× and 1× optical magnification systems. The final pixel size resulted in 3.1 and 6.2 µm, respectively. The measured characteristic parameters of the PCO.Edge5.5 are in good agreement with the manufacturer specifications. Fast imaging can be achieved using this detection system, but at the price of unavoidable losses in terms of image quality. The way in which the X-ray beam inhomogeneity limited some of the performances of the system is also discussed.

Keywords:  X-ray imaging; image detector; image quality

Year:  2017        PMID: 29091066     DOI: 10.1107/S160057751701222X

Source DB:  PubMed          Journal:  J Synchrotron Radiat        ISSN: 0909-0495            Impact factor:   2.616


  9 in total

1.  High resolution 3D visualization of the spinal cord in a post-mortem murine model.

Authors:  Inna Bukreeva; Victor Asadchikov; Alexey Buzmakov; Marina Chukalina; Anastasya Ingacheva; Nikolay A Korolev; Alberto Bravin; Alberto Mittone; Gabriele E M Biella; Alejandra Sierra; Francesco Brun; Lorenzo Massimi; Michela Fratini; Alessia Cedola
Journal:  Biomed Opt Express       Date:  2020-03-27       Impact factor: 3.732

2.  X-ray multiscale 3D neuroimaging to quantify cellular aging and neurodegeneration postmortem in a model of Alzheimer's disease.

Authors:  Giuseppe Battaglia; Paola Coan; Giacomo E Barbone; Alberto Bravin; Alberto Mittone; Alexandra Pacureanu; Giada Mascio; Paola Di Pietro; Markus J Kraiger; Marina Eckermann; Mariele Romano; Martin Hrabě de Angelis; Peter Cloetens; Valeria Bruno
Journal:  Eur J Nucl Med Mol Imaging       Date:  2022-07-19       Impact factor: 10.057

3.  Hydroxycarboxylic Acid Receptor 2, a Pleiotropically Linked Receptor for the Multiple Sclerosis Drug, Monomethyl Fumarate. Possible Implications for the Inflammatory Response.

Authors:  Benedetta Parodi; Alessia Sanna; Alessia Cedola; Antonio Uccelli; Nicole Kerlero de Rosbo
Journal:  Front Immunol       Date:  2021-05-18       Impact factor: 7.561

4.  In-situ visualization of sound-induced otolith motion using hard X-ray phase contrast imaging.

Authors:  Tanja Schulz-Mirbach; Margie Olbinado; Alexander Rack; Alberto Mittone; Alberto Bravin; Roland R Melzer; Friedrich Ladich; Martin Heß
Journal:  Sci Rep       Date:  2018-02-15       Impact factor: 4.379

5.  Imaging atelectrauma in Ventilator-Induced Lung Injury using 4D X-ray microscopy.

Authors:  Luca Fardin; Ludovic Broche; Goran Lovric; Alberto Mittone; Olivier Stephanov; Anders Larsson; Alberto Bravin; Sam Bayat
Journal:  Sci Rep       Date:  2021-02-19       Impact factor: 4.379

6.  Foam-like phantoms for comparing tomography algorithms.

Authors:  Daniël M Pelt; Allard A Hendriksen; Kees Joost Batenburg
Journal:  J Synchrotron Radiat       Date:  2022-01-01       Impact factor: 2.616

7.  Characterizing pearls structures using X-ray phase-contrast and neutron imaging: a pilot study.

Authors:  D Micieli; D Di Martino; M Musa; L Gori; A Kaestner; A Bravin; A Mittone; R Navone; G Gorini
Journal:  Sci Rep       Date:  2018-08-14       Impact factor: 4.379

8.  Auditory chain reaction: Effects of sound pressure and particle motion on auditory structures in fishes.

Authors:  Tanja Schulz-Mirbach; Friedrich Ladich; Alberto Mittone; Margie Olbinado; Alberto Bravin; Isabelle P Maiditsch; Roland R Melzer; Petr Krysl; Martin Heß
Journal:  PLoS One       Date:  2020-03-27       Impact factor: 3.240

9.  Convolutional neuronal networks combined with X-ray phase-contrast imaging for a fast and observer-independent discrimination of cartilage and liver diseases stages.

Authors:  Johannes Stroebel; Annie Horng; Marco Armbruster; Alberto Mittone; Maximilian Reiser; Alberto Bravin; Paola Coan
Journal:  Sci Rep       Date:  2020-11-17       Impact factor: 4.379

  9 in total

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