Literature DB >> 29091034

Updating the Diabetic Foot Treatment Algorithm: Recommendations on Treatment Using Advanced Medicine and Therapies.

Peter Blume1, Stephanie Wu2.   

Abstract

OBJECTIVE: Since the last diabetic foot ulcer (DFU) treatment algorithm was published in 2002, new options for diagnostic testing and treatments have been developed. This study seeks to update the DFU treatment algorithm to include new options available in diagnostic testing and treatment.
MATERIALS AND METHODS: A computerized literature search of peer-reviewed articles published between January 2003 and January 2016 was conducted using MEDLINE (PubMed), EMBASE, and the Cochrane Library. Diabetic foot ulcer treatment algorithms were reviewed and changes recommended based on current standards of care, new treatment modalities, and clinical experience.
RESULTS: A multidisciplinary approach is recommended to address potential underlying problems. A visual inspection, foot pulse palpation, skin temperature measurement, and shoe gear, gait, orthopedic, neurologic, and vascular exams are recommended. Appropriate offloading and continuing diabetes education are included as treatment for all DFUs. If calluses or increased foot pressure are present, preventative care is necessary to prevent further tissue breakdown. If infection is present, treatment should follow the Infectious Diseases Society of America diabetic foot infection guidelines. As the DFU severity increases, advanced wound dressings and advanced wound therapies should be employed. In acute/chronic and acute/urgent DFUs, debridement, amputation, and skin grafting may be required.
CONCLUSIONS: Treatment for DFUs should start when a possible pre-ulcer is noticed. This prophylactic treatment may reduce development of more severe DFUs. Once a DFU has developed, care should be optimized for both the patient and the wound bed. While these treatment recommendations are focused solely on DFUs, they may be expanded for use in other foot/leg pressure ulcers.

Entities:  

Mesh:

Year:  2017        PMID: 29091034

Source DB:  PubMed          Journal:  Wounds        ISSN: 1044-7946            Impact factor:   1.546


  9 in total

Review 1.  The role of gel wound dressings loaded with stem cells in the treatment of diabetic foot ulcers.

Authors:  Xionglin Chen; Jianfang Wu; Xiaoming Cao; He Jiang; Zhiren Wu; Zidu Zeng; Hui Chen; Jie Zhang
Journal:  Am J Transl Res       Date:  2021-12-15       Impact factor: 4.060

Review 2.  Diabetic Foot scientific activities in Endocrinology and Metabolism Research Institute.

Authors:  Maryam Aalaa; Mahnaz Sanjari; Ensieh Nasli Esfahani; Rash Atlasi; Bagher Larijani; Mohammad Reza Mohajeri-Tehrani; Neda Mehrdad; Mohammad Reza Amini
Journal:  J Diabetes Metab Disord       Date:  2021-06-15

3.  A multidisciplinary team approach in Iranian diabetic foot research group.

Authors:  Maryam Aalaa; Mahnaz Sanjari; Mohammad Reza Mohajeri-Tehrani; Neda Mehrdad; Mohammad Reza Amini
Journal:  J Diabetes Metab Disord       Date:  2019-11-09

4.  Surgical OFF-LOADING of the diabetic foot.

Authors:  Luca Dalla Paola; Anna Carone; Marialuisa Valente; Mariano Palena; Giuseppe Scavone
Journal:  J Clin Orthop Trauma       Date:  2021-01-22

5.  An observational pilot study using a purified reconstituted bilayer matrix to treat non-healing diabetic foot ulcers.

Authors:  David G Armstrong; Dennis P Orgill; Robert D Galiano; Paul M Glat; Jarrod P Kaufman; Marissa J Carter; Charles M Zelen
Journal:  Int Wound J       Date:  2020-04-07       Impact factor: 3.315

6.  Low-frequency ultrasound enhances vascular endothelial growth factor expression, thereby promoting the wound healing in diabetic rats.

Authors:  Lang Chen; Qian Zheng; Xianzhuo Chen; Jun Wang; Lan Wang
Journal:  Exp Ther Med       Date:  2019-09-25       Impact factor: 2.447

7.  Can supernatant from immortalized adipose tissue MSC replace cell therapy? An in vitro study in chronic wounds model.

Authors:  Honorata Kraskiewicz; Maria Paprocka; Aleksandra Bielawska-Pohl; Agnieszka Krawczenko; Kinga Panek; Judyta Kaczyńska; Agnieszka Szyposzyńska; Mateusz Psurski; Piotr Kuropka; Aleksandra Klimczak
Journal:  Stem Cell Res Ther       Date:  2020-01-21       Impact factor: 6.832

8.  Static Magnetic Field Accelerates Diabetic Wound Healing by Facilitating Resolution of Inflammation.

Authors:  Wenlong Shang; Guilin Chen; Yinxiu Li; Yujuan Zhuo; Yuhong Wang; Zhicai Fang; Ying Yu; Huiwen Ren
Journal:  J Diabetes Res       Date:  2019-11-30       Impact factor: 4.011

Review 9.  Therapeutic strategies for chronic wound infection.

Authors:  Yi-Fan Liu; Peng-Wen Ni; Yao Huang; Ting Xie
Journal:  Chin J Traumatol       Date:  2021-07-06
  9 in total

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