Literature DB >> 29090954

Is p38 MAPK a Dark Force in Right Ventricular Hypertrophy and Failure in Pulmonary Arterial Hypertension?

Rebecca R Vanderpool1, Haiyang Tang1, Franz Rischard1,2, Jason X-J Yuan3,4.   

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Year:  2017        PMID： 29090954      PMCID： PMC5705908          DOI： 10.1165/rcmb.2017-0197ED

Source DB:  PubMed          Journal:  Am J Respir Cell Mol Biol        ISSN： 1044-1549            Impact factor:   6.914


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  11 in total

Review 1.  Right heart adaptation to pulmonary arterial hypertension: physiology and pathobiology.

Authors:  Anton Vonk-Noordegraaf; François Haddad; Kelly M Chin; Paul R Forfia; Steven M Kawut; Joost Lumens; Robert Naeije; John Newman; Ronald J Oudiz; Steve Provencher; Adam Torbicki; Norbert F Voelkel; Paul M Hassoun
Journal:  J Am Coll Cardiol       Date:  2013-12-24       Impact factor: 24.094

2.  A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo.

Authors:  Jennifer Davis; Adam R Burr; Gregory F Davis; Lutz Birnbaumer; Jeffery D Molkentin
Journal:  Dev Cell       Date:  2012-09-27       Impact factor: 12.270

3.  Activation of c-Jun N-terminal kinases and p38-mitogen-activated protein kinases in human heart failure secondary to ischaemic heart disease.

Authors:  S A Cook; P H Sugden; A Clerk
Journal:  J Mol Cell Cardiol       Date:  1999-08       Impact factor: 5.000

4.  Upregulated expression of STIM2, TRPC6, and Orai2 contributes to the transition of pulmonary arterial smooth muscle cells from a contractile to proliferative phenotype.

Authors:  Ruby A Fernandez; Jun Wan; Shanshan Song; Kimberly A Smith; Yali Gu; Mohammad Tauseef; Haiyang Tang; Ayako Makino; Dolly Mehta; Jason X-J Yuan
Journal:  Am J Physiol Cell Physiol       Date:  2015-02-11       Impact factor: 4.249

5.  Sildenafil treatment in established right ventricular dysfunction improves diastolic function and attenuates interstitial fibrosis independent from afterload.

Authors:  Marinus A Borgdorff; Beatrijs Bartelds; Michael G Dickinson; Maarten P H van Wiechen; Paul Steendijk; Maartje de Vroomen; Rolf M F Berger
Journal:  Am J Physiol Heart Circ Physiol       Date:  2014-05-30       Impact factor: 4.733

6.  NADPH oxidase-dependent redox signaling in human heart failure: relationship between the left and right ventricle.

Authors:  Chiara Nediani; Elisabetta Borchi; Carla Giordano; Serena Baruzzo; Vanessa Ponziani; Mariangela Sebastiani; Paolo Nassi; Alessandro Mugelli; Giulia d'Amati; Elisabetta Cerbai
Journal:  J Mol Cell Cardiol       Date:  2007-01-31       Impact factor: 5.000

7.  The reversal of pulmonary vascular remodeling through inhibition of p38 MAPK-alpha: a potential novel anti-inflammatory strategy in pulmonary hypertension.

Authors:  Alistair C Church; Damien H Martin; Roger Wadsworth; Gareth Bryson; Andrew J Fisher; David J Welsh; Andrew J Peacock
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2015-05-29       Impact factor: 5.464

8.  Novel mechanisms of sildenafil in pulmonary hypertension involving cytokines/chemokines, MAP kinases and Akt.

Authors:  Tamas Kiss; Krisztina Kovacs; Andras Komocsi; Adrienn Tornyos; Petra Zalan; Balazs Sumegi; Ferenc Gallyas; Krisztina Kovacs
Journal:  PLoS One       Date:  2014-08-18       Impact factor: 3.240

9.  Losmapimod, a novel p38 mitogen-activated protein kinase inhibitor, in non-ST-segment elevation myocardial infarction: a randomised phase 2 trial.

Authors:  L Kristin Newby; Michael S Marber; Chiara Melloni; Lea Sarov-Blat; Laura H Aberle; Philip E Aylward; Gengqian Cai; Robbert J de Winter; Christian W Hamm; John F Heitner; Raymond Kim; Amir Lerman; Manesh R Patel; Jean-Francois Tanguay; John J Lepore; Hussein R Al-Khalidi; Dennis L Sprecher; Christopher B Granger
Journal:  Lancet       Date:  2014-06-12       Impact factor: 79.321

10.  Deletion of Fn14 receptor protects from right heart fibrosis and dysfunction.

Authors:  Tatyana Novoyatleva; Yves Schymura; Wiebke Janssen; Frederic Strobl; Jakub M Swiercz; Chinmoy Patra; Guido Posern; Astrid Wietelmann; Timothy S Zheng; Ralph T Schermuly; Felix B Engel
Journal:  Basic Res Cardiol       Date:  2013-01-17       Impact factor: 17.165
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  2 in total

1.  Inhibition of Bruton's Tyrosine Kinase Alleviates Monocrotaline-Induced Pulmonary Arterial Hypertension by Modulating Macrophage Polarization.

Authors:  Min Yu; Xuecheng Wu; Liyao Peng; Mingxia Yang; Hong Zhou; Jian Xu; Jingjing Wang; Hong Wang; Weiping Xie; Hui Kong
Journal:  Oxid Med Cell Longev       Date:  2022-08-29       Impact factor: 7.310

2.  Therapeutic Benefit of the Association of Lodenafil with Mesenchymal Stem Cells on Hypoxia-induced Pulmonary Hypertension in Rats.

Authors:  Marina de Moraes Carvalho da Silva; Allan Kardec Nogueira de Alencar; Jaqueline Soares da Silva; Tadeu Lima Montagnoli; Grazielle Fernandes da Silva; Bruna de Souza Rocha; Guilherme Carneiro Montes; Rosália Mendez-Otero; Pedro Moreno Pimentel-Coelho; Juliana F Vasques; Margarete Manhães Trahez; Roberto Takashi Sudo; Gisele Zapata-Sudo
Journal:  Cells       Date:  2020-09-18       Impact factor: 6.600
  2 in total

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