Literature DB >> 29089597

Our microbes not only produce antibiotics, they also overproduce amino acids.

Sergio Sanchez1, Romina Rodríguez-Sanoja1, Allison Ramos2, Arnold L Demain2.   

Abstract

Fermentative production of amino acids is an important goal of modern biotechnology. Through fermentation, micro-organisms growing on inexpensive carbon and nitrogen sources can produce a wide array of valuable products including amino acids. The amino acid market is $8 billion and mainly impacts the food, pharmaceutical and cosmetics industries. In terms of tons of amino acids produced per year by fermentation, L-glutamate is the most important amino acid produced (3.3 million), followed by L-lysine (2.2 million). The bacteria producing these amino acids are among the top fermentation organisms with respect to titers. Corynebacterium glutamicum is the best producer.The Journal of Antibiotics advance online publication, 1 November 2017; doi:10.1038/ja.2017.142.

Entities:  

Year:  2017        PMID: 29089597     DOI: 10.1038/ja.2017.142

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN: 0021-8820            Impact factor:   2.649


  51 in total

1.  Pushing product formation to its limit: metabolic engineering of Corynebacterium glutamicum for L-leucine overproduction.

Authors:  Michael Vogt; Sabine Haas; Simon Klaffl; Tino Polen; Lothar Eggeling; Jan van Ooyen; Michael Bott
Journal:  Metab Eng       Date:  2013-12-11       Impact factor: 9.783

2.  Metabolic engineering of Escherichia coli W3110 for the production of L-methionine.

Authors:  Hua Li; Bao Shi Wang; You Ran Li; Liang Zhang; Zhong Yang Ding; Zheng Hua Gu; Gui Yang Shi
Journal:  J Ind Microbiol Biotechnol       Date:  2016-11-14       Impact factor: 3.346

Review 3.  Microbial production of amino acids and derived chemicals: synthetic biology approaches to strain development.

Authors:  Volker F Wendisch
Journal:  Curr Opin Biotechnol       Date:  2014-06-09       Impact factor: 9.740

4.  Deletion of odhA or pyc improves production of γ-aminobutyric acid and its precursor L-glutamate in recombinant Corynebacterium glutamicum.

Authors:  Nannan Wang; Yalan Ni; Feng Shi
Journal:  Biotechnol Lett       Date:  2015-03-24       Impact factor: 2.461

Review 5.  Metabolic engineering of Escherichia coli and Corynebacterium glutamicum for biotechnological production of organic acids and amino acids.

Authors:  Volker F Wendisch; Michael Bott; Bernhard J Eikmanns
Journal:  Curr Opin Microbiol       Date:  2006-04-17       Impact factor: 7.934

6.  Efficient aspartic acid production by a psychrophile-based simple biocatalyst.

Authors:  Takahisa Tajima; Mai Hamada; Yutaka Nakashimada; Junichi Kato
Journal:  J Ind Microbiol Biotechnol       Date:  2015-08-08       Impact factor: 3.346

7.  Characterization of bifunctional L-glutathione synthetases from Actinobacillus pleuropneumoniae and Actinobacillus succinogenes for efficient glutathione biosynthesis.

Authors:  Jianhua Yang; Wei Li; Dezheng Wang; Hui Wu; Zhimin Li; Qin Ye
Journal:  Appl Microbiol Biotechnol       Date:  2016-03-21       Impact factor: 4.813

8.  Fermentative production of tryptophan by a stable recombinant strain of Corynebacterium glutamicum with a modified serine-biosynthetic pathway.

Authors:  M Ikeda; K Nakanishi; K Kino; R Katsumata
Journal:  Biosci Biotechnol Biochem       Date:  1994-04       Impact factor: 2.043

Review 9.  The threonine story.

Authors:  Vladimir G Debabov
Journal:  Adv Biochem Eng Biotechnol       Date:  2003       Impact factor: 2.635

10.  L-Tryptophan: Basic Metabolic Functions, Behavioral Research and Therapeutic Indications.

Authors:  Dawn M Richard; Michael A Dawes; Charles W Mathias; Ashley Acheson; Nathalie Hill-Kapturczak; Donald M Dougherty
Journal:  Int J Tryptophan Res       Date:  2009-03-23
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  11 in total

1.  Dynamic Alterations in Yak Rumen Bacteria Community and Metabolome Characteristics in Response to Feed Type.

Authors:  Chang Liu; Hao Wu; Shujie Liu; Shatuo Chai; Qingxiang Meng; Zhenming Zhou
Journal:  Front Microbiol       Date:  2019-05-22       Impact factor: 6.064

2.  Role of gut microbiota in regulating gastrointestinal dysfunction and motor symptoms in a mouse model of Parkinson's disease.

Authors:  Yogesh Bhattarai; Jie Si; Meng Pu; Owen A Ross; Pamela J McLean; Lisa Till; William Moor; Madhusudan Grover; Karunya K Kandimalla; Kara G Margolis; Gianrico Farrugia; Purna C Kashyap
Journal:  Gut Microbes       Date:  2021-01-01

Review 3.  Interplay of Good Bacteria and Central Nervous System: Cognitive Aspects and Mechanistic Considerations.

Authors:  Mahmoud Salami
Journal:  Front Neurosci       Date:  2021-02-11       Impact factor: 4.677

4.  The Serum and Fecal Metabolomic Profiles of Growing Kittens Treated with Amoxicillin/Clavulanic Acid or Doxycycline.

Authors:  Evangelia M Stavroulaki; Jan S Suchodolski; Rachel Pilla; Geoffrey T Fosgate; Chi-Hsuan Sung; Jonathan Lidbury; Jörg M Steiner; Panagiotis G Xenoulis
Journal:  Animals (Basel)       Date:  2022-01-29       Impact factor: 2.752

5.  Enantiomer discrimination in β-phenylalanine degradation by a newly isolated Paraburkholderia strain BS115 and type strain PsJN.

Authors:  Oliver Buß; Sarah-Marie Dold; Pascal Obermeier; Dennis Litty; Delphine Muller; Jens Grüninger; Jens Rudat
Journal:  AMB Express       Date:  2018-09-21       Impact factor: 3.298

Review 6.  d-glutamate and Gut Microbiota in Alzheimer's Disease.

Authors:  Chun-Hung Chang; Chieh-Hsin Lin; Hsien-Yuan Lane
Journal:  Int J Mol Sci       Date:  2020-04-11       Impact factor: 5.923

Review 7.  Recent Progress in Lab-On-a-Chip Systems for the Monitoring of Metabolites for Mammalian and Microbial Cell Research.

Authors:  Esma Dervisevic; Kellie L Tuck; Nicolas H Voelcker; Victor J Cadarso
Journal:  Sensors (Basel)       Date:  2019-11-18       Impact factor: 3.576

8.  High-Level Production of Lysine in the Yeast Saccharomyces cerevisiae by Rational Design of Homocitrate Synthase.

Authors:  Shota Isogai; Tomonori Matsushita; Hiroyuki Imanishi; Jirasin Koonthongkaew; Yoichi Toyokawa; Akira Nishimura; Xiao Yi; Romas Kazlauskas; Hiroshi Takagi
Journal:  Appl Environ Microbiol       Date:  2021-07-13       Impact factor: 4.792

Review 9.  Microbiota and Pain: Save Your Gut Feeling.

Authors:  Chiara Morreale; Ilia Bresesti; Annalisa Bosi; Andreina Baj; Cristina Giaroni; Massimo Agosti; Silvia Salvatore
Journal:  Cells       Date:  2022-03-11       Impact factor: 6.600

10.  Scale-up economics for cultured meat.

Authors:  David Humbird
Journal:  Biotechnol Bioeng       Date:  2021-06-17       Impact factor: 4.530

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