Literature DB >> 29089596

Professor Hamao Umezawa opened up a new road for the development of molecularly targeted therapeutic drugs for cancers.

Masaya Imoto1.   

Abstract

This issue is dedicated to Prof Hamao Umezawa in appreciation of his great contributions to pioneering research on antibiotics targeting oncogenes.The Journal of Antibiotics advance online publication, 1 November 2017; doi:10.1038/ja.2017.139.

Entities:  

Year:  2017        PMID： 29089596     DOI： 10.1038/ja.2017.139

Source DB:  PubMed          Journal:  J Antibiot (Tokyo)        ISSN： 0021-8820            Impact factor:   2.649


  20 in total

1.  Sarkomycin, an anti-tumor substance produced by streptomyces.

Authors:  H UMEZAWA; T TAKEUCHI; K NITTA; T YAMAMOTO; S YAMAOKA
Journal:  J Antibiot (Tokyo)       Date:  1953-04       Impact factor: 2.649

2.  Effective synthesis of erbstatin and its analogs.

Authors:  K Isshiki; M Imoto; T Takeuchi; H Umezawa; T Tsuchida; T Yoshioka; K Tatsuta
Journal:  J Antibiot (Tokyo)       Date:  1987-08       Impact factor: 2.649

3.  Kinetic studies of tyrosine kinase inhibition by erbstatin.

Authors:  M Imoto; K Umezawa; K Isshiki; S Kunimoto; T Sawa; T Takeuchi; H Umezawa
Journal:  J Antibiot (Tokyo)       Date:  1987-10       Impact factor: 2.649

4.  Inhibition of tyrosine protein kinase by synthetic erbstatin analogs.

Authors:  K Isshiki; M Imoto; T Sawa; K Umezawa; T Takeuchi; H Umezawa; T Tsuchida; T Yoshioka; K Tatsuta
Journal:  J Antibiot (Tokyo)       Date:  1987-08       Impact factor: 2.649

5.  Characterization of platelet-derived growth factor-stimulated phosphorylation in cell membranes.

Authors:  L J Pike; D F Bowen-Pope; R Ross; E G Krebs
Journal:  J Biol Chem       Date:  1983-08-10       Impact factor: 5.157

6.  Characterization of the receptor for platelet-derived growth factor on human fibroblasts. Demonstration of an intimate relationship with a 185,000-Dalton substrate for the platelet-derived growth factor-stimulated kinase.

Authors:  C H Heldin; B Ek; L Rönnstrand
Journal:  J Biol Chem       Date:  1983-08-25       Impact factor: 5.157

7.  Phenotypic change from transformed to normal induced by benzoquinonoid ansamycins accompanies inactivation of p60src in rat kidney cells infected with Rous sarcoma virus.

Authors:  Y Uehara; M Hori; T Takeuchi; H Umezawa
Journal:  Mol Cell Biol       Date:  1986-06       Impact factor: 4.272

8.  Avian sarcoma virus-transforming protein, pp60src shows protein kinase activity specific for tyrosine.

Authors:  M S Collett; A F Purchio; R L Erikson
Journal:  Nature       Date:  1980-05-15       Impact factor: 49.962

9.  Identification of phosphotyrosine as a product of epidermal growth factor-activated protein kinase in A-431 cell membranes.

Authors:  H Ushiro; S Cohen
Journal:  J Biol Chem       Date:  1980-09-25       Impact factor: 5.157

10.  Screening of agents which convert 'transformed morphology' of Rous sarcoma virus-infected rat kidney cells to 'normal morphology': identification of an active agent as herbimycin and its inhibition of intracellular src kinase.

Authors:  Y Uehara; M Hori; T Takeuchi; H Umezawa
Journal:  Jpn J Cancer Res       Date:  1985-08
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