Literature DB >> 29089255

Huntington disease care: From the past to the present, to the future.

T A Mestre1, K Shannon2.   

Abstract

INTRODUCTION: Huntington disease is a progressive neurodegenerative disorder without a cure. Its clinical presentation makes complex the care of patients with HD, further impacted by the progressive loss of dependence and disability. Intuitively, HD management calls for multispecialty care.
METHODS: Literature review and expert-based statement.
RESULTS: Chorea is the only indication for symptomatic treatments in HD. Surgical therapies are experimental, and exercise-based physical interventions have been assessed but in small feasibility studies. In HD, multispecialty care requires the active involvement of physicians, therapists, social workers and nutritionists. In about half of the HD clinics, a multidisciplinary case review is offered. It is still unknown what is the care delivery model that is best for HD. Palliative care is an important concept in HD care focusing in quality of life, considering physical, psychosocial, and spiritual problems. Palliative care may delay nursing home placement in advanced HD.
CONCLUSION: There is a support for multispecialty care in HD, but more evidence needs to be generated through clinical research. The implementation of technology in the multispecialty care of patients with HD has a significant potential for reducing the care burden for families and the healthcare team, and to secure a wider care delivery.
Copyright © 2017. Published by Elsevier Ltd.

Entities:  

Keywords:  Care; Huntington disease; Integration; Multidisciplinary; Technology

Mesh:

Year:  2017        PMID: 29089255     DOI: 10.1016/j.parkreldis.2017.08.009

Source DB:  PubMed          Journal:  Parkinsonism Relat Disord        ISSN: 1353-8020            Impact factor:   4.891


  3 in total

1.  Therapeutic Use of Music, Dance, and Rhythmic Auditory Cueing for Patients with Huntington's Disease: A Systematic Review.

Authors:  Anna E Schwartz; Marleen R van Walsem; Are Brean; Jan C Frich
Journal:  J Huntingtons Dis       Date:  2019

Review 2.  Insights into the Effects of the Dental Stem Cell Secretome on Nerve Regeneration: Towards Cell-Free Treatment.

Authors:  Rohaina Che Man; Nadiah Sulaiman; Ruszymah Bt Hj Idrus; Shahrul Hisham Zainal Ariffin; Rohaya Megat Abdul Wahab; Muhammad Dain Yazid
Journal:  Stem Cells Int       Date:  2019-10-24       Impact factor: 5.443

3.  Another Perspective on Huntington's Disease: Disease Burden in Family Members and Pre-Manifest HD When Compared to Genotype-Negative Participants from ENROLL-HD.

Authors:  Jannis Achenbach; Carsten Saft
Journal:  Brain Sci       Date:  2021-12-08
  3 in total

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