| Literature DB >> 29087123 |
Karina J Juárez-Rendón1,2, Gildardo Rivera Sánchez2, Miguel Á Reyes-López2, José E García-Ortiz3, Virgilio Bocanegra-García2, Iliana Guardiola-Avila4, María L Altamirano-García5.
Abstract
Alopecia areata (AA) is a dermatological disease characterized by non-scarring hair loss of the scalp and/or body, with an unpredictable and variable evolution in the patients in which, despite multidisciplinary efforts, its etiology is not entirely known, although some evidence suggests that environmental, immunological and genetic factors could be generating the disease. The aim of this review is to provide an updated panorama of the clinical characteristics, diagnosis and treatment of AA, to analyze the mechanisms that could participate in its etiology, as well as to review some of the most important genetic variants that could confer susceptibility to the development of this disease. Sociedad Argentina de Pediatría.Entities:
Keywords: Alopecia Areata; genes; susceptibility
Mesh:
Year: 2017 PMID: 29087123 DOI: 10.5546/aap.2017.eng.e404
Source DB: PubMed Journal: Arch Argent Pediatr ISSN: 0325-0075 Impact factor: 0.635