Rosalía Vicentín1, Marta Wagener2, Alejandro B Pais1, Mónica Contreras3, Marina Orsi4. 1. Hospital de Niños Dr. Orlando Alassia, Santa Fe, Argentina. vicentinrosalia@gmail.com. 2. Hospital de Niños Dr. Orlando Alassia, Santa Fe, Argentina. 3. Hospital de Pediatría "Prof. Dr. Juan P. Garrahan", Ciudad Autónoma de Buenos Aires, Argentina. 4. Hospital Italiano de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina.
Abstract
INTRODUCTION: Inflammatory bowel disease (IBD) includes ulcerative colitis (UC) and Crohn's disease (CD). IBD diagnosis has become increasingly common in pediatrics but its incidence is unknown in Argentina. The objective of this study was to determine the annual incidence of IBD in children and adolescents younger than 18 years in Argentina, its epidemiological aspects, and clinical presentations. POPULATION AND METHODS: Prospective, observational, multicenter study conducted in Argentina. Children and adolescents younger than 18 years from public and private facilities, diagnosed with IBD between June 1st, 2012 and May 31st, 2013 were included via a web protocol. RESULTS: Seventeen sites participated in the study; 50 patients were recruited from 10 sites. IBD incidence was 0.4/100 000 among individuals <18 years; CD, 20; UC, 25; and idiopathic IBD, 5. Distribution by sex: 26 boys and 24 girls. Patients' mean age at diagnosis was 9.7 years, and delay in the diagnosis was 16.5 months. The most common symptoms and signs were chronic diarrhea with blood and/or mucus, abdominal pain, and weight loss. Growth retardation was less common than expected. Extraintestinal manifestations were observed in 24% of UC cases and in 25% of CD cases. The most common location of CD was the ileum and colon, and of UC was the entire colon (pancolonic). There were no cases with severe UC. CONCLUSIONS: The incidence was lower than that reported in other registries. We recommend the development of an ongoing registry, to establish the incidence of IBD, but also to serve as backup for referring facilities where this disease is diagnosed and treated. Sociedad Argentina de Pediatría
INTRODUCTION: Inflammatory bowel disease (IBD) includes ulcerative colitis (UC) and Crohn's disease (CD). IBD diagnosis has become increasingly common in pediatrics but its incidence is unknown in Argentina. The objective of this study was to determine the annual incidence of IBD in children and adolescents younger than 18 years in Argentina, its epidemiological aspects, and clinical presentations. POPULATION AND METHODS: Prospective, observational, multicenter study conducted in Argentina. Children and adolescents younger than 18 years from public and private facilities, diagnosed with IBD between June 1st, 2012 and May 31st, 2013 were included via a web protocol. RESULTS: Seventeen sites participated in the study; 50 patients were recruited from 10 sites. IBD incidence was 0.4/100 000 among individuals <18 years; CD, 20; UC, 25; and idiopathic IBD, 5. Distribution by sex: 26 boys and 24 girls. Patients' mean age at diagnosis was 9.7 years, and delay in the diagnosis was 16.5 months. The most common symptoms and signs were chronic diarrhea with blood and/or mucus, abdominal pain, and weight loss. Growth retardation was less common than expected. Extraintestinal manifestations were observed in 24% of UC cases and in 25% of CD cases. The most common location of CD was the ileum and colon, and of UC was the entire colon (pancolonic). There were no cases with severe UC. CONCLUSIONS: The incidence was lower than that reported in other registries. We recommend the development of an ongoing registry, to establish the incidence of IBD, but also to serve as backup for referring facilities where this disease is diagnosed and treated. Sociedad Argentina de Pediatría
Authors: Aymane Ajbar; Eleanor Cross; Simbarashe Matoi; Charles A Hay; Libby M Baines; Benjamin Saunders; Adam D Farmer; James A Prior Journal: Dig Dis Sci Date: 2022-03-14 Impact factor: 3.199
Authors: Santiago Jiménez Treviño; Gemma Pujol Muncunill; Rafael Martín-Masot; Alejandro Rodríguez Martínez; Oscar Segarra Cantón; Luis Peña Quintana; Honorio Armas Ramos; Francisco Javier Eizaguirre Arocena; Josefa Barrio Torres; José Ignacio García Burriel; Luis Ortigosa Castillo; Ester Donat Aliaga; Vanesa Crujeiras Martínez; Patricia Barros García; Gonzalo Botija Arcos; Juan Manuel Bartolomé Porro; Mercedes Juste Ruiz; Carlos Ochoa Sangrador; Zuriñe García Casales; Gonzalo Galicia Poblet; Pablo Oliver Goicolea; Helena Lorenzo Garrido; Ruth García Romero; Enrique La Orden Izquierdo; David Pérez Solis; Víctor Manuel Navas-López; Juan José Díaz Martin; Javier Martín de Carpi Journal: Front Pediatr Date: 2020-10-15 Impact factor: 3.418