Karan Sarode 1 , Saad S Hussain 2 , Alan Tyroch 3 , Debabrata Mukherjee 2 . Show Affiliations »
Abstract
BACKGROUND: Viscoelastic tests (VETs) such as thromboelastography, rotational thromboelastography, and the Sonoclot Analyzer assess the entire process of clot formation through dissolution in real-time, and may provide additional therapeutic value to conventional laboratory coagulation tests. With the ability to obtain rapid results and identify specific coagulopathies, VETs has been examined in a variety of clinical scenarios, including cardiac surgery, trauma, obstetric emergencies, and liver transplant. CONCLUSION: This review provides a summary of clinical trials utilizing VETs in the aforementioned clinical scenarios, and suggests that VETs have demonstrated a capability to identify coagulopathies, utility in guiding algorithms to reduce the amount of transfusions, and a limited ability to predict bleeding events or mortality. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.
BACKGROUND: Viscoelastic tests (VETs) such as thromboelastography, rotational thromboelastography , and the Sonoclot Analyzer assess the entire process of clot formation through dissolution in real-time, and may provide additional therapeutic value to conventional laboratory coagulation tests. With the ability to obtain rapid results and identify specific coagulopathies , VETs has been examined in a variety of clinical scenarios, including cardiac surgery, trauma , obstetric emergencies , and liver transplant. CONCLUSION: This review provides a summary of clinical trials utilizing VETs in the aforementioned clinical scenarios, and suggests that VETs have demonstrated a capability to identify coagulopathies , utility in guiding algorithms to reduce the amount of transfusions, and a limited ability to predict bleeding events or mortality. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.
Entities: Disease
Keywords:
Viscoelastic tests; clot analyzer; coagulation tests.; coagulopathy; surgery; trauma
Mesh: See more »
Year: 2017
PMID: 29086703 DOI: 10.2174/1871529X17666171030120851
Source DB: PubMed Journal: Cardiovasc Hematol Disord Drug Targets ISSN: 1871-529X