| Literature DB >> 29083898 |
Chi Thanh Ma1, Taeyong Eom2, Eunji Cho, Bo Wu3, Tae Ryong Kim, Ki Bong Oh, Sang Beom Han2, Sung Won Kwon, Jeong Hill Park.
Abstract
Four new and five known sesquiterpenoids were isolated from the agarwood of Aquilaria malaccensis. Aquilanols A and B (1 and 2) have an unprecedented macrocyclic humulene structure with a bicyclic 7/10 ring system. Compound 2 was obtained as a scalemic mixture that was resolved by HPLC analysis using a chiral column. Their structures were deduced based on spectroscopic data analysis, and the absolute configurations were unambiguously determined by X-ray crystallographic data and ECD spectroscopic analysis. A putative biosynthetic pathway of these sesquiterpenoids is proposed.Entities:
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Year: 2017 PMID： 29083898 DOI： 10.1021/acs.jnatprod.7b00462
Source DB: PubMed Journal: J Nat Prod ISSN： 0163-3864 Impact factor: 4.050