| Literature DB >> 29083164 |
Jianguo Wang1,2, Xinggui Gu1, Pengfei Zhang1, Xiaobo Huang3, Xiaoyan Zheng1, Ming Chen1, Haitao Feng1, Ryan T K Kwok1, Jacky W Y Lam1, Ben Zhong Tang1,4,5.
Abstract
Recent years have witnessed the significant role of anion-π+ interactions in many areas, which potentially brings the opportunity for the development of aggregation-induced emission (AIE) systems. Here, a new strategy that utilized anion-π+ interactions to block detrimental π-π stacking was first proposed to develop inherent-charged AIE systems. Two AIE-active luminogens, namely, 1,2,3,4-tetraphenyloxazolium (TPO-P) and 2,3,5-triphenyloxazolium (TriPO-PN), were successfully synthesized. Comprehensive techniques such as single-crystal analysis, theoretical calculation, and conductivity measurement were used to illustrate the effects of anion-π+ interactions on the AIE feature. Their analogues tetraphenylfuran (TPF) and 2,4,5-triphenyloxazole (TriPO-C) without anion-π+ interactions suffered from the aggregation-caused emission quenching in the aggregate state, demonstrating the important role of anion-π+ interactions in suppressing π-π stacking. TriPO-PN was biocompatible and could specifically target lysosome in fluorescence turn-on and wash-free manners. This suggested that it was a promising contrast agent for bioimaging.Entities:
Year: 2017 PMID： 29083164 DOI： 10.1021/jacs.7b10150
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419