Literature DB >> 29082426

Anxiety Disorders and Obsessive-Compulsive Disorder in Individuals with Autism Spectrum Disorder.

Valentina Postorino1,2, Connor M Kerns3, Giacomo Vivanti3, Jessica Bradshaw1,2, Martina Siracusano4, Luigi Mazzone5.   

Abstract

PURPOSE OF REVIEW: This review aims to synthesize the most recent research on anxiety disorders and obsessive-compulsive disorder (OCD) in individuals with autism spectrum disorder (ASD) and discuss the relationship between these conditions and challenges for assessment. Furthermore, implications for treatment and future directions are discussed. RECENT
FINDINGS: Research suggests that anxiety disorders and OCD are highly prevalent in individuals with ASD. However, the significant overlap of ASD features with anxiety and OCD symptomology makes differential diagnosis of these disorders particularly challenging. Though several treatments for anxiety have been adapted for youth with ASD (e.g., cognitive behavior therapy), pharmacological treatments and treatments for adults are still marked undeveloped. Despite the high prevalence of anxiety disorders and OCD in ASD and some recent advances in assessment and treatment, research is needed to clarify the multifaceted relationship of these conditions and develop tailored assessment and treatment approaches appropriate for a full range of individuals with ASD.

Entities:  

Keywords:  Anxiety; Autism spectrum disorder; Obsessive-compulsive disorder; Repetitive behaviors

Mesh:

Year:  2017        PMID: 29082426      PMCID: PMC5846200          DOI: 10.1007/s11920-017-0846-y

Source DB:  PubMed          Journal:  Curr Psychiatry Rep        ISSN: 1523-3812            Impact factor:   5.285


  73 in total

1.  Parent-rated anxiety symptoms in children with pervasive developmental disorders: frequency and association with core autism symptoms and cognitive functioning.

Authors:  Denis G Sukhodolsky; Lawrence Scahill; Kenneth D Gadow; L Eugene Arnold; Michael G Aman; Christopher J McDougle; James T McCracken; Elaine Tierney; Susan Williams White; Luc Lecavalier; Benedetto Vitiello
Journal:  J Abnorm Child Psychol       Date:  2007-08-03

2.  Obsessions and compulsions in Asperger syndrome and high-functioning autism.

Authors:  Ailsa J Russell; David Mataix-Cols; Martin Anson; Declan G M Murphy
Journal:  Br J Psychiatry       Date:  2005-06       Impact factor: 9.319

3.  Examining shared and unique aspects of Social Anxiety Disorder and Autism Spectrum Disorder using factor analysis.

Authors:  Susan W White; Bethany C Bray; Thomas H Ollendick
Journal:  J Autism Dev Disord       Date:  2012-05

4.  Not to be overshadowed or overlooked: functional impairments associated with comorbid anxiety disorders in youth with ASD.

Authors:  Connor M Kerns; Philip C Kendall; Hana Zickgraf; Martin E Franklin; Judith Miller; John Herrington
Journal:  Behav Ther       Date:  2014-03-20

5.  The Relationship Between Adverse Childhood Events, Resiliency and Health Among Children with Autism.

Authors:  Bethany Rigles
Journal:  J Autism Dev Disord       Date:  2017-01

6.  Repetitive behaviour in children with high functioning autism and obsessive compulsive disorder.

Authors:  Fiona Zandt; Margot Prior; Michael Kyrios
Journal:  J Autism Dev Disord       Date:  2007-02

7.  Psychometric properties of the Screen for Child Anxiety Related Emotional Disorders (SCARED): a replication study.

Authors:  B Birmaher; D A Brent; L Chiappetta; J Bridge; S Monga; M Baugher
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  1999-10       Impact factor: 8.829

8.  Obsessive-compulsive traits in children and adolescents with Asperger syndrome.

Authors:  Liliana Ruta; Diego Mugno; Valentina Genitori D'Arrigo; Benedetto Vitiello; Luigi Mazzone
Journal:  Eur Child Adolesc Psychiatry       Date:  2009-06-26       Impact factor: 4.785

9.  Brief report: cognitive processing of own emotions in individuals with autistic spectrum disorder and in their relatives.

Authors:  Elisabeth Hill; Sylvie Berthoz; Uta Frith
Journal:  J Autism Dev Disord       Date:  2004-04

10.  Obsessive-Compulsive Disorder in Adults with High-Functioning Autism Spectrum Disorder: What Does Self-Report with the OCI-R Tell Us?

Authors:  Tim Cadman; Debbie Spain; Patrick Johnston; Ailsa Russell; David Mataix-Cols; Michael Craig; Quinton Deeley; Dene Robertson; Clodagh Murphy; Nicola Gillan; C Ellie Wilson; Maria Mendez; Christine Ecker; Eileen Daly; James Findon; Karen Glaser; Francesca Happé; Declan Murphy
Journal:  Autism Res       Date:  2015-02-07       Impact factor: 5.216

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  25 in total

1.  Felt but not seen: Observed restricted repetitive behaviors are associated with self-report-but not parent-report-obsessive-compulsive disorder symptoms in youth with autism spectrum disorder.

Authors:  Lee A Santore; Alan Gerber; Ayla N Gioia; Rebecca Bianchi; Fanny Talledo; Tara S Peris; Matthew D Lerner
Journal:  Autism       Date:  2020-03-13

Review 2.  Neurodevelopmental Disorders Affecting Sociability: Recent Research Advances and Future Directions in Autism Spectrum Disorder and Williams Syndrome.

Authors:  Giacomo Vivanti; Taralee Hamner; Nancy Raitano Lee
Journal:  Curr Neurol Neurosci Rep       Date:  2018-10-17       Impact factor: 5.081

3.  ASD/OCD-Linked Protocadherin-10 Regulates Synapse, But Not Axon, Development in the Amygdala and Contributes to Fear- and Anxiety-Related Behaviors.

Authors:  Naosuke Hoshina; Erin M Johnson-Venkatesh; Veronica R Rally; Jaanvi Sant; Miyuki Hoshina; Mariel P Seiglie; Hisashi Umemori
Journal:  J Neurosci       Date:  2022-05-03       Impact factor: 6.709

Review 4.  Comorbid autism spectrum disorder and anxiety disorders: a brief review.

Authors:  Brian A Zaboski; Eric A Storch
Journal:  Future Neurol       Date:  2018-01-17

5.  Neuronal SETD2 activity links microtubule methylation to an anxiety-like phenotype in mice.

Authors:  Matthias Koenning; Xianlong Wang; Menuka Karki; Rahul Kumar Jangid; Sarah Kearns; Durga Nand Tripathi; Michael Cianfrocco; Kristen J Verhey; Sung Yun Jung; Cristian Coarfa; Christopher Scott Ward; Brian Thomas Kalish; Sandra L Grimm; W Kimryn Rathmell; Ricardo Mostany; Ruhee Dere; Matthew Neil Rasband; Cheryl Lyn Walker; In Young Park
Journal:  Brain       Date:  2021-09-04       Impact factor: 15.255

6.  A Data Driven Approach Reveals That Anomalous Motor System Connectivity is Associated With the Severity of Core Autism Symptoms.

Authors:  Daniel E Lidstone; Rebecca Rochowiak; Stewart H Mostofsky; Mary Beth Nebel
Journal:  Autism Res       Date:  2021-01-22       Impact factor: 4.633

7.  Social and emotional characteristics of girls and young women with DDX3X-associated intellectual disability: a descriptive and comparative study.

Authors:  Elise Ng-Cordell; Anna Kolesnik-Taylor; Sinéad O'Brien; Duncan Astle; Gaia Scerif; Kate Baker
Journal:  J Autism Dev Disord       Date:  2022-05-10

8.  Diagnostic- and sex-based differences in depression symptoms in autistic and neurotypical early adolescents.

Authors:  Jessica M Schwartzman; Zachary J Williams; Blythe A Corbett
Journal:  Autism       Date:  2021-06-26

9.  Anxiety Sensitivity Domains are Differently Affected by Social and Non-social Autistic Traits.

Authors:  Chiara Baiano; Gennaro Raimo; Isa Zappullo; Roberta Cecere; Barbara Rauso; Monica Positano; Massimiliano Conson
Journal:  J Autism Dev Disord       Date:  2021-08-10

Review 10.  The Sensory Abnormalities and Neuropsychopathology of Autism and Anxiety.

Authors:  Sirisha K Gara; Ashok G Chhetri; Montaser Alrjoob; Sassi Ashraf Ali Abbasi; Ian H Rutkofsky
Journal:  Cureus       Date:  2020-05-12
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