Literature DB >> 29082285

Murine Bronchoalveolar Lavage.

Fan Sun1,2, Gutian Xiao1,2, Zhaoxia Qu1,2.   

Abstract

A basic Bronchoalveolar lavage (BAL) procedure in mouse is described here. Cells and fluids obtained from BAL can be analyzed by Hema3-staining, immunostaining, Fluorescence-activated cell sorting (FACS), PCR, bicinchoninic acid protein assay, enzyme-linked immunosorbent assay (ELISA), luminex assays, etc., to examine the immune cells, pathogens, proteins such as cytokines/chemokines, and the expression levels of inflammation-related and other genes in the cells. This will help to understand the underlying mechanisms of these lung diseases and develop specific and effective drugs.

Entities:  

Keywords:  Bronchoalveolar lavage; Hema3-staining; Lung cancer

Year:  2017        PMID： 29082285      PMCID： PMC5659634          DOI： 10.21769/BioProtoc.2287

Source DB:  PubMed          Journal:  Bio Protoc        ISSN： 2331-8325


  5 in total

1.  Myeloid STAT3 Promotes Lung Tumorigenesis by Transforming Tumor Immunosurveillance into Tumor-Promoting Inflammation.

Authors:  Jingjiao Zhou; Zhaoxia Qu; Fan Sun; Lei Han; Liwen Li; Shapei Yan; Laura P Stabile; Lin-Feng Chen; Jill M Siegfried; Gutian Xiao
Journal:  Cancer Immunol Res       Date:  2017-01-20       Impact factor: 11.151

2.  Performing Bronchoalveolar Lavage in the Mouse.

Authors:  François Daubeuf; Nelly Frossard
Journal:  Curr Protoc Mouse Biol       Date:  2012-06-01

3.  Interleukin-6 Prevents the Initiation but Enhances the Progression of Lung Cancer.

Authors:  Zhaoxia Qu; Fan Sun; Jingjiao Zhou; Liwen Li; Steven D Shapiro; Gutian Xiao
Journal:  Cancer Res       Date:  2015-06-29       Impact factor: 12.701

4.  NF-κB1 p105 suppresses lung tumorigenesis through the Tpl2 kinase but independently of its NF-κB function.

Authors:  F Sun; Z Qu; Y Xiao; J Zhou; T F Burns; L P Stabile; J M Siegfried; G Xiao
Journal:  Oncogene       Date:  2015-08-24       Impact factor: 9.867

5.  Differential roles of STAT3 in the initiation and growth of lung cancer.

Authors:  Jingjiao Zhou; Zhaoxia Qu; Shapei Yan; Fan Sun; Jeffrey A Whitsett; Steven D Shapiro; Gutian Xiao
Journal:  Oncogene       Date:  2014-10-06       Impact factor: 9.867
  5 in total
  17 in total

1.  Myeloid STAT3 Promotes Lung Tumorigenesis by Transforming Tumor Immunosurveillance into Tumor-Promoting Inflammation.

Authors:  Jingjiao Zhou; Zhaoxia Qu; Fan Sun; Lei Han; Liwen Li; Shapei Yan; Laura P Stabile; Lin-Feng Chen; Jill M Siegfried; Gutian Xiao
Journal:  Cancer Immunol Res       Date:  2017-01-20       Impact factor: 11.151

2.  NF-κB RelA renders tumor-associated macrophages resistant to and capable of directly suppressing CD8+ T cells for tumor promotion.

Authors:  Liwen Li; Lei Han; Fan Sun; Jingjiao Zhou; Kim C Ohaegbulam; Xudong Tang; Xingxing Zang; Kris A Steinbrecher; Zhaoxia Qu; Gutian Xiao
Journal:  Oncoimmunology       Date:  2018-02-27       Impact factor: 8.110

3.  A humanized mouse model of chronic COVID-19 to evaluate disease mechanisms and treatment options.

Authors:  Esen Sefik; Ben Israelow; Jun Zhao; Rihao Qu; Eric Song; Haris Mirza; Eleanna Kaffe; Stephanie Halene; Eric Meffre; Yuval Kluger; Michel Nussenzweig; Craig Wilen; Akiko Iwasaki; Richard A Flavell
Journal:  Res Sq       Date:  2021-03-17

4.  Inflammasome activation in infected macrophages drives COVID-19 pathology.

Authors:  Esen Sefik; Rihao Qu; Caroline Junqueira; Eleanna Kaffe; Haris Mirza; Jun Zhao; J Richard Brewer; Ailin Han; Holly R Steach; Benjamin Israelow; Holly N Blackburn; Sofia E Velazquez; Y Grace Chen; Stephanie Halene; Akiko Iwasaki; Eric Meffre; Michel Nussenzweig; Judy Lieberman; Craig B Wilen; Yuval Kluger; Richard A Flavell
Journal:  Nature       Date:  2022-04-28       Impact factor: 69.504

5.  Respiratory tissue-associated commensal bacteria offer therapeutic potential against pneumococcal colonization.

Authors:  Soner Yildiz; João P Pereira Bonifacio Lopes; Matthieu Bergé; Víctor González-Ruiz; Damian Baud; Joachim Kloehn; Inês Boal-Carvalho; Olivier P Schaeren; Michael Schotsaert; Lucy J Hathaway; Serge Rudaz; Patrick H Viollier; Siegfried Hapfelmeier; Patrice Francois; Mirco Schmolke
Journal:  Elife       Date:  2020-12-08       Impact factor: 8.140

6.  Isolation and Long-term Cultivation of Mouse Alveolar Macrophages.

Authors:  Clara Jana-Lui Busch; Jérémy Favret; Laufey Geirsdóttir; Kaaweh Molawi; Michael H Sieweke
Journal:  Bio Protoc       Date:  2019-07-20

7.  Impact of Influenza A Virus Shutoff Proteins on Host Immune Responses.

Authors:  Megan M Dunagan; Kala Hardy; Toru Takimoto
Journal:  Vaccines (Basel)       Date:  2021-06-10

8.  Quantitative Structure-Activity Relationship Models for Predicting Inflammatory Potential of Metal Oxide Nanoparticles.

Authors:  Yang Huang; Xuehua Li; Shujuan Xu; Huizhen Zheng; Lili Zhang; Jingwen Chen; Huixiao Hong; Rebecca Kusko; Ruibin Li
Journal:  Environ Health Perspect       Date:  2020-06-12       Impact factor: 9.031

9.  Impact of Influenza on Pneumococcal Vaccine Effectiveness during Streptococcus pneumoniae Infection in Aged Murine Lung.

Authors:  Ermias Jirru; Stefi Lee; Rebecca Harris; Jianjun Yang; Soo Jung Cho; Heather Stout-Delgado
Journal:  Vaccines (Basel)       Date:  2020-06-11

10.  An mRNA SARS-CoV-2 Vaccine Employing Charge-Altering Releasable Transporters with a TLR-9 Agonist Induces Neutralizing Antibodies and T Cell Memory.

Authors:  Ole A W Haabeth; Julian J K Lohmeyer; Adrienne Sallets; Timothy R Blake; Idit Sagiv-Barfi; Debra K Czerwinski; Blaine McCarthy; Abigail E Powell; Paul A Wender; Robert M Waymouth; Ronald Levy
Journal:  ACS Cent Sci       Date:  2021-06-18       Impact factor: 14.553
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