| Literature DB >> 29080411 |
Shi-Li Yan1, Yan-Hong Li1, Xuan-Qin Chen1, Dan Liu1, Chin-Ho Chen2, Rong-Tao Li3.
Abstract
Six previously undescribed diterpenoids, named euphorantins S-T and euphorneroids A-D, including ingol and ent-atisane types, along with eleven known diterpenoids, were isolated from Euphorbia neriifolia. Their structures were elucidated on the basis of extensive NMR analysis and high resolution mass spectrometry. Euphorneroid D and ent-3-oxoatisan-16α,17-acetonide exhibited moderate anti-HIV-1 activities, with EC50 values of 34 μM (SI = 2.3) and 24 μM (SI = 1.9), respectively.Entities:
Keywords: Anti-HIV activity; Euphorantins S-T; Euphorbia neriifolia; Euphorbiaceae; Euphorneroids A-D
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Year: 2017 PMID： 29080411 DOI： 10.1016/j.phytochem.2017.10.006
Source DB: PubMed Journal: Phytochemistry ISSN： 0031-9422 Impact factor: 4.072