Literature DB >> 29079158

Clostridium difficile in Older Adults.

Curtis J Donskey1.   

Abstract

Recent increases in the incidence of Clostridium difficile infection (CDI) have been observed in all age groups, but the elderly have been disproportionately affected and long-term care facilities (LTCFs) have borne a significant proportion of the increasing burden. Recurrences are common in older adults and may have significant adverse effects on quality of life. Ensuring appropriate diagnostic testing and management is challenging for older adults in the community and in LTCFs. This review focuses on current concepts related to the epidemiology, diagnosis, and management of CDI in older adults. Published by Elsevier Inc.

Entities:  

Keywords:  C difficile infection; Elderly; Fecal microbiota transplant; Long-term care facility

Mesh：

Substances：

Year:  2017        PMID： 29079158     DOI： 10.1016/j.idc.2017.07.003

Source DB:  PubMed          Journal:  Infect Dis Clin North Am        ISSN： 0891-5520            Impact factor:   5.982


  6 in total

1.  Aging impairs protective host defenses against Clostridioides (Clostridium) difficile infection in mice by suppressing neutrophil and IL-22 mediated immunity.

Authors:  Alex G Peniche; Jennifer K Spinler; Prapaporn Boonma; Tor C Savidge; Sara M Dann
Journal:  Anaerobe       Date:  2018-08-09       Impact factor: 3.331

2.  Proton pump inhibitors and 180-day mortality in the elderly after Clostridium difficile treatment.

Authors:  Evan Stuart Bradley; Emily Howe; Xun Wu; John P Haran
Journal:  Gut Pathog       Date:  2019-06-13       Impact factor: 4.181

3.  Gastrointestinal Tolerance and Microbiome Response to Snacks Fortified with Pea Hull Fiber: A Randomized Trial in Older Adults.

Authors:  Zainab Alyousif; Daniela Rivero Mendoza; Jérémie Auger; Vanessa De Carvalho; Samantha Amos; Charles Sims; Wendy J Dahl
Journal:  Curr Dev Nutr       Date:  2020-01-17

Review 4.  How Does COVID-19 Pandemic Impact on Incidence of Clostridioides difficile Infection and Exacerbation of Its Gastrointestinal Symptoms?

Authors:  Masoumeh Azimirad; Maryam Noori; Hamideh Raeisi; Abbas Yadegar; Shabnam Shahrokh; Hamid Asadzadeh Aghdaei; Enrico Bentivegna; Paolo Martelletti; Nicola Petrosillo; Mohammad Reza Zali
Journal:  Front Med (Lausanne)       Date:  2021-12-13

Review 5.  The impact of human vaccines on bacterial antimicrobial resistance. A review.

Authors:  Kathrin U Jansen; William C Gruber; Raphael Simon; James Wassil; Annaliesa S Anderson
Journal:  Environ Chem Lett       Date:  2021-09-29       Impact factor: 13.615

6.  New Host-Directed Therapeutics for the Treatment of Clostridioides difficile Infection.

Authors:  Jourdan A Andersson; Alex G Peniche; Cristi L Galindo; Prapaporn Boonma; Jian Sha; Ruth Ann Luna; Tor C Savidge; Ashok K Chopra; Sara M Dann
Journal:  mBio       Date:  2020-03-10       Impact factor: 7.867
  6 in total

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