Literature DB >> 2907790

Central nervous system activity of terpenoids from marine sponge.

R De Pasquale1, C Circosta, F Occhiuto, S De Stefano, S De Rosa.   

Abstract

Some terpenoids extracted from marine sponge: triacetylated disidein, 2-tetraprenyl benzoquinol and 4 hydroxy-3-tetraprenylbenzoic acid 2-polyprenyl benzoquinols, avarol and furospongin-1 were tested by multidimensional Irwin screening and with some tests for analgesic and muscle relaxant activity. The three prenylhydroquinols derivatives and avarol show a good analgesic activity and low toxicity.

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Year:  1988        PMID: 2907790     DOI: 10.1016/s0031-6989(88)80833-6

Source DB:  PubMed          Journal:  Pharmacol Res Commun        ISSN: 0031-6989


  1 in total

1.  Anticonvulsant and analgesic activities of crude extract and its fractions of the defensive secretion from the Mediterranean sponge, Spongia officinalis.

Authors:  Afef Dellai; Hedi Ben Mansour; Audrey Clary-Laroche; Monia Deghrigue; Abderrahman Bouraoui
Journal:  Cancer Cell Int       Date:  2012-04-11       Impact factor: 5.722

  1 in total

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