Literature DB >> 29077479

Illness and intelligence are comparatively strong predictors of individual differences in depressive symptoms following middle age.

Stephen Aichele1, Patrick Rabbitt2, Paolo Ghisletta1,3,4.   

Abstract

OBJECTIVE: We compared the importance of socio-demographic, lifestyle, health, and multiple cognitive measures for predicting individual differences in depressive symptoms in later adulthood.
METHOD: Data came from 6203 community-dwelling older adults (age 41-93 years at study entry) from the United Kingdom. Predictors (36 in total) were assessed up to four times across a period of approximately 12 years. Depressive symptoms were measured with the Geriatric Depression Scale. Statistical methods included multiple imputation (for missing data), random forest analysis (a machine learning approach), and multivariate regression.
RESULTS: On average, depressive symptoms increased gradually following middle age and appeared to accelerate in later life. Individual differences in depressive symptoms were most strongly associated with differences in combined symptoms of physical illness (positive relation) and fluid intelligence (negative relation). The strength of association between depressive symptoms and fluid intelligence was unaffected by differences in health status within a subsample of chronically depressed individuals.
CONCLUSION: Joint consideration of general health status and fluid intelligence may facilitate prediction of depressive symptoms severity during later life and may also serve to identify sub-populations of community-dwelling elders at risk for chronic depression.

Entities:  

Keywords:  Depression; aging; cognition; fluid intelligence; machine learning

Mesh:

Year:  2017        PMID: 29077479     DOI: 10.1080/13607863.2017.1394440

Source DB:  PubMed          Journal:  Aging Ment Health        ISSN: 1360-7863            Impact factor:   3.658


  4 in total

1.  Machine learning assessment of risk factors for depression in later adulthood.

Authors:  Fengqing Zhang; Jiangtao Gou
Journal:  Lancet Reg Health Eur       Date:  2022-05-11

2.  Predictors of depression among middle-aged and older men and women in Europe: A machine learning approach.

Authors:  Elizabeth P Handing; Carolin Strobl; Yuqin Jiao; Leilani Feliciano; Stephen Aichele
Journal:  Lancet Reg Health Eur       Date:  2022-04-29

3.  Fluid Intelligence Predicts Change in Depressive Symptoms in Later Life: The Lothian Birth Cohort 1936.

Authors:  Stephen Aichele; Paolo Ghisletta; Janie Corley; Alison Pattie; Adele M Taylor; John M Starr; Ian J Deary
Journal:  Psychol Sci       Date:  2018-10-25

4.  Dietary Habit Is Associated with Depression and Intelligence: An Observational and Genome-Wide Environmental Interaction Analysis in the UK Biobank Cohort.

Authors:  Bolun Cheng; Xiaomeng Chu; Xuena Yang; Yan Wen; Yumeng Jia; Chujun Liang; Yao Yao; Jing Ye; Shiqiang Cheng; Li Liu; Cuiyan Wu; Feng Zhang
Journal:  Nutrients       Date:  2021-03-31       Impact factor: 5.717

  4 in total

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