Literature DB >> 29076645

Generalised joint hypermobility and knee joint hypermobility: prevalence, knee joint symptoms and health-related quality of life in a Danish adult population.

Tina Junge1,2, Peter Henriksen1,2, Sebrina Hansen1, Lasse Østengaard1, Yvonne M Golightly3,4,5,6, Birgit Juul-Kristensen1.   

Abstract

AIM: Several biomechanical factors, such as knee joint hypermobility (KJH), are suggested to play a role in the etiology of knee joint symptoms and knee osteoarthritis. Nevertheless, the prevalence or consequences of KJH solely or included in the classification of generalized joint hypermobility (GJHk) is unknown for a general population. Therefore, the objectives were to report the prevalence of self-reported GJHk and KJH, as well as the association of these conditions to knee joint symptoms, severity and duration of symptoms, and health-related quality of life (HRQoL) in a Danish adult population.
METHOD: This study is a cross-sectional population-based survey of 2056 Danish adults. Respondents received online questionnaires of GJHk and KJH, knee joint symptoms, the severity and duration of these, as well as HRQoL.
RESULTS: Total response rate was 49% (n = 1006). The prevalence of self-reported GJHk and KJH was 13% and 23%, mostly representing women. More than half of the respondents with GJHk and KJH had knee joint symptoms. The odds for reporting knee joint symptoms, severity of knee joint symptoms and duration of knee joint symptoms were twice as high for respondents with GJHk and KJH. Respondents with GJHk and KJH reported lower HRQoL.
CONCLUSION: GJHk and KJH were frequently reported in the Danish adult population, mostly in women. Respondents with GJHk and KJH were two times more likely to report knee joint-related symptoms such as pain, reduced performance of usual activity and lower HRQoL. The impact of these conditions on HRQoL is comparable with knee osteoarthritis.
© 2017 Asia Pacific League of Associations for Rheumatology and John Wiley & Sons Australia, Ltd.

Entities:  

Keywords:  generalized joint hypermobility; knee joint; pain; quality of life

Mesh:

Year:  2017        PMID: 29076645     DOI: 10.1111/1756-185X.13205

Source DB:  PubMed          Journal:  Int J Rheum Dis        ISSN: 1756-1841            Impact factor:   2.454


  3 in total

1.  Beyond bones: The relevance of variants of connective tissue (hypermobility) to fibromyalgia, ME/CFS and controversies surrounding diagnostic classification: an observational study.

Authors:  Jessica A Eccles; Beth Thompson; Kristy Themelis; Marisa L Amato; Robyn Stocks; Amy Pound; Anna-Marie Jones; Zdenka Cipinova; Lorraine Shah-Goodwin; Jean Timeyin; Charlotte R Thompson; Thomas Batty; Neil A Harrison; Hugo D Critchley; Kevin A Davies
Journal:  Clin Med (Lond)       Date:  2021-01       Impact factor: 2.659

2.  Prevalence, frontal plane knee alignment, and lower limb joint pain and injury in generalized joint hypermobility in Thai physical therapy students.

Authors:  Pawan Chaiparinya; Chitanongk Gaogasigam
Journal:  Reumatologia       Date:  2022-05-18

Review 3.  Generalised joint hypermobility increases ACL injury risk and is associated with inferior outcome after ACL reconstruction: a systematic review.

Authors:  David Sundemo; Eric Hamrin Senorski; Louise Karlsson; Alexandra Horvath; Birgit Juul-Kristensen; Jon Karlsson; Olufemi R Ayeni; Kristian Samuelsson
Journal:  BMJ Open Sport Exerc Med       Date:  2019-11-10
  3 in total

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