| Literature DB >> 2907549 |
C L Chander1, A R Moore, F M Desa, D Howat, D A Willoughby.
Abstract
Endothelin has been shown to suppress increased vascular permeability in the rat at doses of 0.01 pmol. The agonists used were nitric oxide and nitroprusside, which have the same activity as endothelial-derived relaxing factor. Histamine, 5-hydroxytryptamine, platelet activating factor and carrageenan were the other agonists used. It is proposed that endothelin and EDRF act as local hormones produced by endothelial cells to control local vascular permeability.Entities:
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Year: 1988 PMID： 2907549 DOI： 10.1111/j.2042-7158.1988.tb07011.x
Source DB: PubMed Journal: J Pharm Pharmacol ISSN： 0022-3573 Impact factor: 3.765