| Literature DB >> 29075425 |
Ren Cai1, Dan Yang2, Jin Wu2, Liqin Zhang1, Cuichen Wu1, Xigao Chen1, Yanyue Wang1, Shuo Wan1, Fengwei Hou2, Qingyu Yan2, Weihong Tan1,3.
Abstract
Ultrathin two-dimensional (2D) porous Zn(OH)2 nanosheets (PNs) have been fabricated by using one-dimensional Cu nanowires as backbones. PNs have thicknesses of about 3.8 nm and pore sizes of 4~10 nm. To form "smart" porous nanosheets, DNA aptamers were covalently conjugated on the surface of PNs. These ultrathin nanosheets show good biocompatibility, efficient cellular uptake, and promising pH-stimulated drug release.Entities:
Keywords: Aptamer; Cancer cell; Cell-targeted delivery; Porous Zn(OH)2 nanosheets
Year: 2016 PMID: 29075425 PMCID: PMC5654576 DOI: 10.1007/s12274-016-1138-2
Source DB: PubMed Journal: Nano Res ISSN: 1998-0000 Impact factor: 8.897