| Literature DB >> 2907492 |
M Furuhashi1, S Mizutani, O Kurauchi, M Kasugai, O Narita, Y Tomoda.
Abstract
The degradation of opioid peptides by human placental aminopeptidase M was studied by measuring liberated amino acids by high performance liquid chromatography. The purified placental aminopeptidase M actively degraded Met-enkephalin (Met-Enk) and Leu-enkephalin (Leu-Enk) completely into constituent 5 amino acids. The activities as a function of tyrosine liberation were observed for Met-Enk followed by Leu-Enk, beta-neoendorphin, dynorphin, and beta-endorphin.Entities:
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Year: 1988 PMID： 2907492 DOI： 10.1055/s-0029-1210807
Source DB: PubMed Journal: Exp Clin Endocrinol ISSN： 0232-7384