Literature DB >> 29074533

Novel Antithrombotic Drugs on the Horizon: The Ultimate Promise to Prevent Clotting While Avoiding Bleeding.

James D McFadyen1, Karlheinz Peter2.   

Abstract

Keywords:  acute coronary syndromes; anticoagulants; aspirin; fibrin; hemorrhage; platelets; thrombosis

Mesh:

Substances:

Year:  2017        PMID: 29074533     DOI: 10.1161/CIRCRESAHA.117.312012

Source DB:  PubMed          Journal:  Circ Res        ISSN: 0009-7330            Impact factor:   17.367


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  10 in total

Review 1.  Thrombotic Regulation From the Endothelial Cell Perspectives.

Authors:  Miao Wang; Huifeng Hao; Nicholas J Leeper; Liyuan Zhu
Journal:  Arterioscler Thromb Vasc Biol       Date:  2018-06       Impact factor: 8.311

Review 2.  Translational Implications of Platelets as Vascular First Responders.

Authors:  Richard C Becker; Travis Sexton; Susan S Smyth
Journal:  Circ Res       Date:  2018-02-02       Impact factor: 17.367

Review 3.  P2Y12 Antagonists in Cardiovascular Disease-Finding the Best Balance Between Preventing Ischemic Events and Causing Bleeding.

Authors:  Himawan Fernando; James D McFadyen; Xiaowei Wang; James Shaw; Dion Stub; Karlheinz Peter
Journal:  Front Cardiovasc Med       Date:  2022-05-12

4.  Improved Antithrombotic Activity and Diminished Bleeding Side Effect of a PEGylated αIIbβ3 Antagonist, Disintegrin.

Authors:  Yu-Ju Kuo; Yao Tsung Chang; Ching-Hu Chung; Woei-Jer Chuang; Tur-Fu Huang
Journal:  Toxins (Basel)       Date:  2020-06-28       Impact factor: 4.546

Review 5.  Marine Antithrombotics.

Authors:  Rohini Dwivedi; Vitor H Pomin
Journal:  Mar Drugs       Date:  2020-10-13       Impact factor: 5.118

Review 6.  Impact of SMTP Targeting Plasminogen and Soluble Epoxide Hydrolase on Thrombolysis, Inflammation, and Ischemic Stroke.

Authors:  Keiji Hasumi; Eriko Suzuki
Journal:  Int J Mol Sci       Date:  2021-01-19       Impact factor: 5.923

7.  Efficacy and safety of next-generation tick transcriptome-derived direct thrombin inhibitors.

Authors:  Cho Yeow Koh; Norrapat Shih; Christina Y C Yip; Aaron Wei Liang Li; Weiming Chen; Fathiah S Amran; Esther Jia En Leong; Janaki Krishnamoorthy Iyer; Grace Croft; Muhammad Ibrahim Bin Mazlan; Yen-Lin Chee; Eng-Soo Yap; Dougald M Monroe; Maureane Hoffman; Richard C Becker; Dominique P V de Kleijn; Vaishali Verma; Amita Gupta; Vijay K Chaudhary; A Mark Richards; R Manjunatha Kini; Mark Y Chan
Journal:  Nat Commun       Date:  2021-11-25       Impact factor: 14.919

Review 8.  Potentiation of thrombus instability: a contributory mechanism to the effectiveness of antithrombotic medications.

Authors:  Diana A Gorog
Journal:  J Thromb Thrombolysis       Date:  2018-05       Impact factor: 2.300

9.  Structure-guided design of pure orthosteric inhibitors of αIIbβ3 that prevent thrombosis but preserve hemostasis.

Authors:  Brian D Adair; José L Alonso; Johannes van Agthoven; Vincent Hayes; Hyun Sook Ahn; I-Shing Yu; Shu-Wha Lin; Jian-Ping Xiong; Mortimer Poncz; M Amin Arnaout
Journal:  Nat Commun       Date:  2020-01-21       Impact factor: 14.919

Review 10.  Atypical Roles of the Chemokine Receptor ACKR3/CXCR7 in Platelet Pathophysiology.

Authors:  Madhumita Chatterjee
Journal:  Cells       Date:  2022-01-09       Impact factor: 6.600

  10 in total

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