Alexandre Leme Godoy-Santos1, Homero Bruschini2, Jose Cury2, Miguel Srougi2, Cesar de Cesar-Netto3, Lucas F Fonseca3, Nicola Maffulli4. 1. Department of Orthopaedics and Traumatology, University of São Paulo, São Paulo, São Paulo, Brazil. Electronic address: alexandrelemegodoy@gmail.com. 2. Department of Urology, University of São Paulo, São Paulo, São Paulo, Brazil. 3. Department of Orthopedics Foot and Ankle Surgery, Hospital for Special Surgery (HSS), New York, NY. 4. Department of Orthopaedics and Traumatology, Azienda Ospedaliera San Giovanni di Dio e Ruggi d'Aragona, University of Salerno, Salerno, Italy; Centre for Sports and Exercise Medicine, Barts and The London School of Medicine and Dentistry, Mile End Hospital, London, United Kingdom.
Abstract
OBJECTIVE: To evaluate the current evidence and to identify associated risk factors that increase the incidence of this complication. Fluoroquinolone (FQ) has been considered the first-line therapy for uncomplicated urinary infections. FQ has been associated with Achilles tendon disorders, especially during the first month of treatment. METHODS: Data sources searched included PubMed, MEDLINE, and Scopus from January 1988 to June 2017. RESULTS: A total of 79 articles were used, with ciprofloxacin representing the most common drug. CONCLUSION: We found that male gender, advanced age, normal body mass index, chronic renal failure, and concurrent use of corticosteroids increase the risk of Achilles tendon disorders.
OBJECTIVE: To evaluate the current evidence and to identify associated risk factors that increase the incidence of this complication. Fluoroquinolone (FQ) has been considered the first-line therapy for uncomplicated urinary infections. FQ has been associated with Achilles tendon disorders, especially during the first month of treatment. METHODS: Data sources searched included PubMed, MEDLINE, and Scopus from January 1988 to June 2017. RESULTS: A total of 79 articles were used, with ciprofloxacin representing the most common drug. CONCLUSION: We found that male gender, advanced age, normal body mass index, chronic renal failure, and concurrent use of corticosteroids increase the risk of Achilles tendon disorders.