Jennifer J Salinas1, Jennifer M Reingle Gonzalez2, Soham Al Snih3. 1. Department of Epidemiology, Human Genetics, Environmental Sciences, University of Texas Health Science Center at Houston School of Public Health, United States, 1101 N. Campbell St., El Paso, TX 79902, USA. Electronic address: Jennifer.J.Salinas@uth.tmc.edu. 2. Department of Epidemiology, Human Genetics, Environmental Sciences, University of Texas Health Science Center at Houston School of Public Health, 6011 Harry Hines Blvd., Suite V8.112, Dallas, TX 75390, USA. Electronic address: jennifer.reingle@utsouthwestern.edu. 3. Division of Rehabilitation Sciences, School of Health Professions, Internal Medicine, Division of Geriatrics, Sealy Center on Aging Rebecca Sealy Bldg 5.112A, 301 University Blvd. Rt. 0177, Galveston, TX, 77555, USA. Electronic address: soalsnih@utmb.edu.
Abstract
AIMS: To evaluate how depression and diabetes severity impact disability progression among Mexican Americans over a 15-year period. METHODS: We used seven waves of the Hispanic Established Population for the Epidemiologic Study of the Elderly (H-EPESE). Primary disability outcomes included the Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL) scales. Explanatory variables included time since diagnosis with diabetes (no type 2 diabetes, 1-10, 11-20, 21+), an indicator of disease severity, and depression. Longitudinal generalized estimating equation models were used to estimate the relationship between time since diabetes diagnosis, depressive symptoms and ADL and IADL disability progression over a 15-year time period. RESULTS: Years since diabetes diagnosis was associated with more rapid ADL and IADL disability progression compared to those without type 2 diabetes. Depression accelerated the disabling process in participants who were diagnosed with diabetes 11years or more years ago. CONCLUSIONS: Longer duration of diabetes and greater symptoms of depression increase vulnerability for disability among older Mexican American adults.
AIMS: To evaluate how depression and diabetes severity impact disability progression among Mexican Americans over a 15-year period. METHODS: We used seven waves of the Hispanic Established Population for the Epidemiologic Study of the Elderly (H-EPESE). Primary disability outcomes included the Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL) scales. Explanatory variables included time since diagnosis with diabetes (no type 2 diabetes, 1-10, 11-20, 21+), an indicator of disease severity, and depression. Longitudinal generalized estimating equation models were used to estimate the relationship between time since diabetes diagnosis, depressive symptoms and ADL and IADL disability progression over a 15-year time period. RESULTS: Years since diabetes diagnosis was associated with more rapid ADL and IADL disability progression compared to those without type 2 diabetes. Depression accelerated the disabling process in participants who were diagnosed with diabetes 11years or more years ago. CONCLUSIONS: Longer duration of diabetes and greater symptoms of depression increase vulnerability for disability among older Mexican American adults.
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