Carolina Mensi1, Marco Mendola2, Barbara Dallari3, Maryam Sokooti3, Ramin Tabibi4, Luciano Riboldi3, Dario Consonni3. 1. Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan, Italy. Electronic address: carolina.mensi@unimi.it. 2. School of Occupational Medicine, Università degli Studi di Milano, Milan, Italy. 3. Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, Milan, Italy. 4. Abadan School of Medical Sciences, Abadan, Iran.
Abstract
BACKGROUND: We examined characteristics of peritoneal (PEM) and pleural (PLM) mesothelioma in Lombardy, Italy. METHODS: From the Lombardy Mesothelioma Registry we selected PEM (N=300) and PLM (N=5011) cases diagnosed in 2000-2014. We investigated asbestos exposure and presence of asbestosis or pleural plaques. RESULTS: Incidence rates (per 1,000,000 person-years, world standardized) of PEM were 1.2 (men) and 0.9 (women), compared with 22.6 and 8.4 for PLM. Asbestosis (both genders) and pleural plaques (men) were more frequent among PEM cases. Occupational asbestos exposure was similar in PEM and PLM cases. We found higher proportions of PEMs employed in the asbestos cement production. CONCLUSION: The higher frequency of pleural plaques in PEM cases confirm the association between asbestos and peritoneal mesothelioma. The higher proportions of asbestosis and of past employment in the asbestos-cement sector among PEM cases suggest a possible role of high exposures to asbestos in the peritoneal mesothelioma genesis.
BACKGROUND: We examined characteristics of peritoneal (PEM) and pleural (PLM) mesothelioma in Lombardy, Italy. METHODS: From the Lombardy Mesothelioma Registry we selected PEM (N=300) and PLM (N=5011) cases diagnosed in 2000-2014. We investigated asbestos exposure and presence of asbestosis or pleural plaques. RESULTS: Incidence rates (per 1,000,000 person-years, world standardized) of PEM were 1.2 (men) and 0.9 (women), compared with 22.6 and 8.4 for PLM. Asbestosis (both genders) and pleural plaques (men) were more frequent among PEM cases. Occupational asbestos exposure was similar in PEM and PLM cases. We found higher proportions of PEMs employed in the asbestos cement production. CONCLUSION: The higher frequency of pleural plaques in PEM cases confirm the association between asbestos and peritoneal mesothelioma. The higher proportions of asbestosis and of past employment in the asbestos-cement sector among PEM cases suggest a possible role of high exposures to asbestos in the peritoneal mesothelioma genesis.
Authors: Dario Consonni; Cristina Calvi; Sara De Matteis; Dario Mirabelli; Maria Teresa Landi; Neil E Caporaso; Susan Peters; Roel Vermeulen; Hans Kromhout; Barbara Dallari; Angela Cecilia Pesatori; Luciano Riboldi; Carolina Mensi Journal: Occup Environ Med Date: 2019-07-08 Impact factor: 4.402
Authors: Andrea Spinazzè; Dario Consonni; Francesca Borghi; Sabrina Rovelli; Andrea Cattaneo; Carolina Zellino; Barbara Dallari; Angela Cecilia Pesatori; Hans Kromhout; Susan Peters; Luciano Riboldi; Domenico Maria Cavallo; Carolina Mensi Journal: Int J Environ Res Public Health Date: 2022-03-13 Impact factor: 3.390