Literature DB >> 29072375

Efficacy of microneedling with 70% glycolic acid peel vs microneedling alone in treatment of atrophic acne scars-A randomized controlled trial.

Shiwangi Rana1, Vibhu Mendiratta1, Ram Chander1.   

Abstract

BACKGROUND: Microneedling with dermaroller and glycolic acid peels is commonly used for treatment of acne scars.
OBJECTIVE: To compare efficacy of microneedling alone versus combination of microneedling with serial 70% glycolic acid peel in management of atrophic acne scars. METHODS & MATERIALS: Sixty patients with atrophic acne scars were randomized into group 1 receiving microneedling at 0, 6, and 12 weeks and group 2 receiving microneedling at 0, 6, and 12 weeks along with 70% glycolic acid peel at 3, 9, and 15 weeks. Acne scar scoring was performed by a blinded observer using ECCA (Echelle d'evaluation clinique des cicatrices d'acne) scoring at baseline and after 22 weeks. Additionally, patients were asked to grade the improvement in acne scars and skin texture on visual analogue scale (VAS).
RESULTS: Of 60 patients, 52 completed the 22-week study period. The decrement from baseline in mean ECCA score was more in group 2 as compared to group 1 (39.65±2.50 vs 29.58±0.18; P<.001). Group 2 also showed more improvement in skin texture as compared to group 1 on VAS.
CONCLUSION: Addition of sequential 70% glycolic acid peel to microneedling gives better scar improvement as compared to microneedling alone. In addition to this, it also improves skin texture.
© 2017 Wiley Periodicals, Inc.

Entities:  

Keywords:  acne scars; glycolic acid peel; microneedling

Mesh:

Substances:

Year:  2017        PMID: 29072375     DOI: 10.1111/jocd.12377

Source DB:  PubMed          Journal:  J Cosmet Dermatol        ISSN: 1473-2130            Impact factor:   2.696


  4 in total

1.  A Comparison of Microneedling versus Glycolic Acid Chemical Peel for the Treatment of Acne Scarring.

Authors:  Fatima Ishfaq; Rohan Shah; Shawana Sharif; Nadia Waqas; Marielle Jamgochian; Babar Rao
Journal:  J Clin Aesthet Dermatol       Date:  2022-06

Review 2.  Microneedling for the Treatment of Scars: An Update for Clinicians.

Authors:  Margit L W Juhasz; Joel L Cohen
Journal:  Clin Cosmet Investig Dermatol       Date:  2020-12-22

Review 3.  A Comprehensive Review of Non-Energy-Based Treatments for Atrophic Acne Scarring.

Authors:  Curtis Tam; Jeffrey Khong; Kevin Tam; Ruslan Vasilev; Wesley Wu; Salar Hazany
Journal:  Clin Cosmet Investig Dermatol       Date:  2022-03-14

4.  Microneedling in the treatment of atrophic scars: A systematic review of randomised controlled trials.

Authors:  Irma Bernadette S Sitohang; Sondang Aemilia Pandjaitan Sirait; Jose Suryanegara
Journal:  Int Wound J       Date:  2021-02-03       Impact factor: 3.315

  4 in total

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