Literature DB >> 29064028

Mother-to-infant transmission of hepatitis B virus: challenges and perspectives.

Yi-Fen Shih1, Chun-Jen Liu2,3,4.   

Abstract

Chronic hepatitis B virus (HBV) infection due to perinatal mother-to-infant transmission (MTIT) remains a serious global health problem. Despite passive-active immunoprophylaxis using hepatitis B vaccination with or without hepatitis B immunoglobulin (HBIg), up to 8-10% of newborns still acquire HBV infection. Understanding the mechanisms of MTIT is essential for the interruption of HBV transmission. There are three possible routes of transmission: intrauterine transmission, transmission during delivery (intrapartum) and postnatal transmission through close contact or breast milk (postpartum). Overall, positivity for hepatitis B e antigen (HBeAg) and the high viral load of the mothers are the two most important risk factors related to MTIT of HBV. This article briefly reviews the viral factors related to MTIT of HBV and discusses the issues that warrant further investigation.

Entities:  

Keywords:  Hepatitis B virus; Transmission; Viral factor

Mesh：

Substances：

Year:  2017        PMID： 29064028     DOI： 10.1007/s12072-017-9831-0

Source DB:  PubMed          Journal:  Hepatol Int        ISSN： 1936-0533            Impact factor:   6.047


  22 in total

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Authors:  Ding-Shinn Chen
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Review 3.  Management of mother-to-child transmission of hepatitis B virus: Propositions and challenges.

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Journal:  Semin Liver Dis       Date:  2013-06-08       Impact factor: 6.115

5.  Mother-to-infant transmission of hepatitis B virus infection: significance of maternal viral load and strategies for intervention.

Authors:  Wan-Hsin Wen; Mei-Hwei Chang; Lu-Lu Zhao; Yen-Hsuan Ni; Hong-Yuan Hsu; Jia-Feng Wu; Pei-Jer Chen; Ding-Shinn Chen; Huey-Ling Chen
Journal:  J Hepatol       Date:  2013-02-26       Impact factor: 25.083

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Authors:  Norah A Terrault; Natalie H Bzowej; Kyong-Mi Chang; Jessica P Hwang; Maureen M Jonas; M Hassan Murad
Journal:  Hepatology       Date:  2015-11-13       Impact factor: 17.425

9.  Towards complete eradication of hepatitis B infection from perinatal transmission: review of the mechanisms of in utero infection and the use of antiviral treatment during pregnancy.

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Journal:  Eur J Obstet Gynecol Reprod Biol       Date:  2013-03-05       Impact factor: 2.435

Review 10.  Vertical transmission of hepatitis B virus: challenges and solutions.

Authors:  Ivan Gentile; Guglielmo Borgia
Journal:  Int J Womens Health       Date:  2014-06-10
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  7 in total

Review 1.  Dynamic profile of the HBeAg-anti-HBe system in acute and chronic hepatitis B virus infection: A clinical-laboratory approach.

Authors:  Robério Amorim de Almeida Pondé
Journal:  Mol Biol Rep       Date:  2020-12-09       Impact factor: 2.316

2.  The Role of Autophagy in the Mother-to-Child Transmission of Pregnant Women With a High Level of HBV DNA.

Authors:  Hong Gao; Ling Xu; Zihao Fan; Xiangying Zhang; Zhongping Duan; Feng Ren
Journal:  Front Cell Infect Microbiol       Date:  2022-04-22       Impact factor: 6.073

3.  Clinical, Pathological and Genetic Characteristics of Pediatric Hepatocellular Carcinoma Associated with Hepatitis B Virus Infection.

Authors:  Pan Zhao; Yinying Lu; Chunya Wang; Limin Wang; Jinfeng Li; Meina Li
Journal:  J Hepatocell Carcinoma       Date:  2021-05-10

4.  Coronavirus disease 2019 among pregnant Chinese women: case series data on the safety of vaginal birth and breastfeeding.

Authors:  Y Wu; C Liu; L Dong; C Zhang; Y Chen; J Liu; C Zhang; C Duan; H Zhang; B W Mol; C-L Dennis; T Yin; J Yang; H Huang
Journal:  BJOG       Date:  2020-05-26       Impact factor: 6.531

5.  Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2: A Systematic Review.

Authors:  Ziyi Yang; Yi Liu
Journal:  Am J Perinatol       Date:  2020-05-13       Impact factor: 1.862

6.  The association of adverse outcomes in the mother with disease progression in offspring in families with clusters of hepatitis B virus infection and unfavorable prognoses in Northwest China.

Authors:  Yuan Yang; Li Jin; Zhen Tian; Dandan Guo; Naijuan Yao; Qian Li; Zicheng Jiang; Daokun Yang; Xianmei Tang; Hongbin Li; Yingli He; Jinfeng Liu; Tianyan Chen; Yingren Zhao
Journal:  Medicine (Baltimore)       Date:  2018-09       Impact factor: 1.817

7.  Viral Infections During Pregnancy: The Big Challenge Threatening Maternal and Fetal Health.

Authors:  Wenzhe Yu; Xiaoqian Hu; Bin Cao
Journal:  Matern Fetal Med       Date:  2021-12-09
  7 in total

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