Differences between chick and turkey embryos in sensitivity to 3,3',4,4'-tetrachloro-biphenyl and in concentration/affinity of the hepatic receptor for 2,3,7,8-tetrachlorodibenzo-p-dioxin.

1. 3,3',4,4'-Tetrachlorobiphenyl (TCB) was 20-100 times more toxic in chick embryos than in turkey embryos when injected into eggs. 2. The ED50-value for induction of AHH activity by TCB in the liver of early chick and turkey embryos was estimated to be 0.6 and 6 micrograms/kg egg, respectively. 3. In both species alpha-naphthoflavone was more effective than metyrapone at inhibiting basal and TCB-induced AHH activities. 4. The TCDD receptor was detected in the liver of 7-day-old chick embryos, while it was not found in 9-day-old turkey embryo liver.