Literature DB >> 29058230

A facile and regioselective one-pot synthesis of novel pyrazolo[1[Formula: see text],5[Formula: see text]:1,2]pyrrolo[3,4-b]quinoline-2,3-dicarboxylate hybrids via intramolecular Wittig reaction.

Tahere Hosseyni Largani1, Gholamhasan Imanzadeh2, Nader Noroozi Pesyan3, Ertan Şahin4, Amir Nasser Shamkhali1, Behrouz Notash5.   

Abstract

The regioselective syntheses of novel pyrazolo[1[Formula: see text],5[Formula: see text]:1,2]pyrrolo[3,4-b]quinoline-2,3-dicarboxylates (6a-l) from pyrrolo([3,4-b]quinolin-2(3H)-yl)benzamides through an intramolecular Wittig reaction are described. This protocol takes advantages of mild conditions, simple workup and high yield which make this method attractive for the synthesis of these hybrid of pyrazolo[1[Formula: see text],5[Formula: see text]:1,2]pyrrolo[3,4-b]quinolines.

Entities:  

Keywords:  Hybrid molecules; One-pot synthesis; Pyrazole; Pyrrolo[3,4-b]quinoline; Regioselective; Wittig reaction

Mesh：

Substances：

Year:  2017        PMID： 29058230     DOI： 10.1007/s11030-017-9784-1

Source DB:  PubMed          Journal:  Mol Divers        ISSN： 1381-1991            Impact factor:   2.943


  15 in total

1.  Preparation and chemistry of 3/5-halogenopyrazoles.

Authors:  Yves L Janin
Journal:  Chem Rev       Date:  2012-05-01       Impact factor: 60.622

2.  Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density.

Authors: 
Journal:  Phys Rev B Condens Matter       Date:  1988-01-15

3.  Design, synthesis and biological evaluation of novel 1,2,3-triazolyl β-hydroxy alkyl/carbazole hybrid molecules.

Authors:  Mohammad Navid Soltani Rad; Somayeh Behrouz; Marzieh Behrouz; Akram Sami; Mehdi Mardkhoshnood; Ali Zarenezhad; Elham Zarenezhad
Journal:  Mol Divers       Date:  2016-06-08       Impact factor: 2.943

Review 4.  From 2000 to mid-2010: a fruitful decade for the synthesis of pyrazoles.

Authors:  Santos Fustero; María Sánchez-Roselló; Pablo Barrio; Antonio Simón-Fuentes
Journal:  Chem Rev       Date:  2011-08-01       Impact factor: 60.622

5.  Tri- and tetrasubstituted pyrazole derivates: regioisomerism switches activity from p38MAP kinase to important cancer kinases.

Authors:  Bassam Abu Thaher; Martina Arnsmann; Frank Totzke; Jan E Ehlert; Michael H G Kubbutat; Christoph Schächtele; Markus O Zimmermann; Pierre Koch; Frank M Boeckler; Stefan A Laufer
Journal:  J Med Chem       Date:  2012-01-17       Impact factor: 7.446

6.  Urea/thiourea: efficient, inexpensive and reusable catalysts for the synthesis of pyrazole derivatives with 2-iminothiazolidin-4-one and 2,4-thiazolidinediones under solvent-free conditions.

Authors:  Veera Swamy Konkala; Pramod Kumar Dubey
Journal:  Mol Divers       Date:  2017-01-04       Impact factor: 2.943

7.  Palladium-catalyzed coupling of pyrazole triflates with arylboronic acids.

Authors:  Curt A Dvorak; Dale A Rudolph; Sandy Ma; Nicholas I Carruthers
Journal:  J Org Chem       Date:  2005-05-13       Impact factor: 4.354

Review 8.  Biological activities of quinoline derivatives.

Authors:  Suresh Kumar; Sandhya Bawa; Himanshu Gupta
Journal:  Mini Rev Med Chem       Date:  2009-12       Impact factor: 3.862

Review 9.  Chloroquine and its analogs: a new promise of an old drug for effective and safe cancer therapies.

Authors:  V Raja Solomon; Hoyun Lee
Journal:  Eur J Pharmacol       Date:  2009-10-15       Impact factor: 4.432

Review 10.  Hybrids: a new paradigm to treat Alzheimer's disease.

Authors:  Manjinder Singh; Maninder Kaur; Navriti Chadha; Om Silakari
Journal:  Mol Divers       Date:  2015-09-02       Impact factor: 2.943
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