Literature DB >> 29057384

Concise Review: Current and Emerging Biomarkers of Nephrotoxicity.

Elijah J Weber1, Jonathan Himmelfarb2, Edward J Kelly1.   

Abstract

The kidney is a primary organ for filtration of the blood and elimination of drugs and xenobiotics. These active reabsorptive and secretory processes can result in acute kidney injury as a result of these concentrative properties. Classic measures of acute kidney injury are hampered by their ability to accurately assess function before irreversible damage has occurred. This review will discuss efforts to refine the clinical utility of standard biomarkers as well as the development of novel biomarkers of nephrotoxicity.

Entities:  

Keywords:  Acute Kidney Injury; Biomarkers; Nephrotoxicity

Year:  2017        PMID： 29057384      PMCID： PMC5647884          DOI： 10.1016/j.cotox.2017.03.002

Source DB:  PubMed          Journal:  Curr Opin Toxicol        ISSN： 2468-2020


  46 in total

Review 1.  Acute Dialysis Quality Initiative II: the Vicenza conference.

Authors:  Rinaldo Bellomo; John A Kellum; Ravindra Mehta; Paul M Palevsky; Claudio Ronco
Journal:  Curr Opin Crit Care       Date:  2002-12       Impact factor: 3.687

2.  Incidence, outcomes, and comparisons across definitions of AKI in hospitalized individuals.

Authors:  Xiaoxi Zeng; Gearoid M McMahon; Steven M Brunelli; David W Bates; Sushrut S Waikar
Journal:  Clin J Am Soc Nephrol       Date:  2013-10-31       Impact factor: 8.237

3.  Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury.

Authors:  T Ichimura; J V Bonventre; V Bailly; H Wei; C A Hession; R L Cate; M Sanicola
Journal:  J Biol Chem       Date:  1998-02-13       Impact factor: 5.157

4.  Plasma and urinary heme oxygenase-1 in AKI.

Authors:  Richard A Zager; Ali C M Johnson; Kirsten Becker
Journal:  J Am Soc Nephrol       Date:  2012-03-22       Impact factor: 10.121

5.  KIM-1 and NGAL as biomarkers of nephrotoxicity induced by gentamicin in rats.

Authors:  Qi-hui Luo; Meng-lu Chen; Feng-jiao Sun; Zheng-li Chen; Ming-yang Li; Wen Zeng; Li Gong; An-chun Cheng; Xi Peng; Jing Fang; Li Tang; Yi Geng
Journal:  Mol Cell Biochem       Date:  2014-08-03       Impact factor: 3.396

6.  Risk of acute kidney injury associated with the use of fluoroquinolones.

Authors:  Steven T Bird; Mahyar Etminan; James M Brophy; Abraham G Hartzema; Joseph A C Delaney
Journal:  CMAJ       Date:  2013-06-03       Impact factor: 8.262

7.  Urine liver-type fatty acid-binding protein and kidney injury molecule-1 in HIV-infected patients receiving combined antiretroviral treatment based on tenofovir.

Authors:  Elżbieta Jabłonowska; Kamila Wójcik; Anna Piekarska
Journal:  AIDS Res Hum Retroviruses       Date:  2013-11-22       Impact factor: 2.205

8.  Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury.

Authors:  Ravindra L Mehta; John A Kellum; Sudhir V Shah; Bruce A Molitoris; Claudio Ronco; David G Warnock; Adeera Levin
Journal:  Crit Care       Date:  2007       Impact factor: 9.097

9.  The Usefulness of Determining Neutrophil Gelatinase-Associated Lipocalin Concentration Excreted in the Urine in the Evaluation of Cyclosporine A Nephrotoxicity in Children with Nephrotic Syndrome.

Authors:  Ewa Gacka; Marcin Życzkowski; Rafał Bogacki; Andrzej Paradysz; Lidia Hyla-Klekot
Journal:  Dis Markers       Date:  2016-12-26       Impact factor: 3.434

Review 10.  Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism.

Authors:  Agnieszka Loboda; Milena Damulewicz; Elzbieta Pyza; Alicja Jozkowicz; Jozef Dulak
Journal:  Cell Mol Life Sci       Date:  2016-04-21       Impact factor: 9.261
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  6 in total

Review 1.  Tissue Culture Models of AKI: From Tubule Cells to Human Kidney Organoids.

Authors:  Julie Bejoy; Eddie S Qian; Lauren E Woodard
Journal:  J Am Soc Nephrol       Date:  2022-01-14       Impact factor: 10.121

2.  In silico approaches in organ toxicity hazard assessment: Current status and future needs for predicting heart, kidney and lung toxicities.

Authors:  Arianna Bassan; Vinicius M Alves; Alexander Amberg; Lennart T Anger; Lisa Beilke; Andreas Bender; Autumn Bernal; Mark T D Cronin; Jui-Hua Hsieh; Candice Johnson; Raymond Kemper; Moiz Mumtaz; Louise Neilson; Manuela Pavan; Amy Pointon; Julia Pletz; Patricia Ruiz; Daniel P Russo; Yogesh Sabnis; Reena Sandhu; Markus Schaefer; Lidiya Stavitskaya; David T Szabo; Jean-Pierre Valentin; David Woolley; Craig Zwickl; Glenn J Myatt
Journal:  Comput Toxicol       Date:  2021-09-13

Review 3.  Emerging Kidney Models to Investigate Metabolism, Transport, and Toxicity of Drugs and Xenobiotics.

Authors:  Piyush Bajaj; Swapan K Chowdhury; Robert Yucha; Edward J Kelly; Guangqing Xiao
Journal:  Drug Metab Dispos       Date:  2018-08-03       Impact factor: 3.922

4.  In vitro toxicological assessment of free 3-MCPD and select 3-MCPD esters on human proximal tubule HK-2 cells.

Authors:  Miriam E Mossoba; Mapa S T Mapa; Magali Araujo; Yang Zhao; Brenna Flannery; Thomas Flynn; Jessica Sprando; Paddy Wiesenfeld; Robert L Sprando
Journal:  Cell Biol Toxicol       Date:  2019-11-05       Impact factor: 6.691

Review 5.  Potential Protective Effects of Antioxidants against Cyclophosphamide-Induced Nephrotoxicity.

Authors:  Muluken Altaye Ayza; Kaleab Alemayehu Zewdie; Elias Fitsum Yigzaw; Solomon Gashaw Ayele; Bekalu Amare Tesfaye; Gebrehiwot Gebremedhin Tafere; Muzey Gebreyohannes Abrha
Journal:  Int J Nephrol       Date:  2022-04-16

6.  Gallic and Hesperidin Ameliorate Electrolyte Imbalances in AlCl3-Induced Nephrotoxicity in Wistar Rats.

Authors:  Tajudeen Olabisi Obafemi
Journal:  Biochem Res Int       Date:  2022-10-10
  6 in total

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