Marienke van Middelkoop1, Kim L Bennell2, Michael J Callaghan3, Natalie J Collins4, Philip G Conaghan5, Kay M Crossley6, Joost J F A Eijkenboom7, Rianne A van der Heijden8, Rana S Hinman2, David J Hunter9, Duncan E Meuffels10, Kathryn Mills11, Edwin H G Oei8, Jos Runhaar7, Dieuwke Schiphof7, Joshua J Stefanik12, Sita M A Bierma-Zeinstra13. 1. Department of General Practice, Erasmus MC University Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands. Electronic address: m.vanmiddelkoop@erasmusmc.nl. 2. Department of Physiotherapy, Centre for Health, Exercise and Sports Medicine, School of Health Sciences, The University of Melbourne, Melbourne, Victoria, Australia. 3. Department of Health Professions, Manchester Metropolitan University, Manchester, UK. 4. School of Health and Rehabilitation Sciences, The University of Queensland, Brisbane, Australia. 5. Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, UK; NIHR Leeds Biomedical Research Centre, Leeds, UK. 6. La Trobe Sport and Exercise Medicine Research Centre, School of Allied Health, La Trobe University, Melbourne, Victoria, Australia. 7. Department of General Practice, Erasmus MC University Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands. 8. Department of Radiology and Nuclear Medicine, Erasmus MC University Medical Center, Rotterdam, The Netherlands. 9. Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia; Rheumatology Department, Royal North Shore Hospital, Sydney, Australia. 10. Department of Orthopaedic Surgery, Erasmus MC University Medical Center, Rotterdam, The Netherlands. 11. Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia. 12. Northeastern University, Bouvé College of Health Sciences, Boston , MA. 13. Department of General Practice, Erasmus MC University Medical Center, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands; Department of Orthopaedic Surgery, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
Abstract
OBJECTIVE: To present the current status of knowledge in the field of patellofemoral (PF) osteoarthritis (OA) and formulate a research agenda in order to guide future research on this topic. DESIGN: A 1-day meeting was organized with the aim to bring together international experts in the field to discuss the current state of knowledge on PF OA. Experts from multiple disciplines were invited based on their scientific publications in the field of PF OA and interest in the subject. Topics discussed include the diagnosis, impact, prognosis, and treatment of PF OA. METHODS: Following context-setting presentations, an interactive discussion was held in order to achieve consensus on the PF OA topics of interest: (1) diagnosis and definition; (2) burden; (3) outcome measures; (4) prognosis; (5) risk factors, and (6) treatment. Groups of meeting attendees reviewed the literature on these topics and narratively summarized the current state of knowledge, and each group formulated research agenda items relevant to the specific topics of interest. Each consortium member consequently ranked the importance of all items on a 0-10 Numerical Rating Scale (NRS) (10 = extremely important, to 0 = not at all important). RESULTS: After ranking all formulated items on importance, 6 of the 28 research agenda items formulated received an average of 7.5 points on the NRS. The most highly ranked items covered the fields of treatment, diagnosis, and definition of PF OA. CONCLUSIONS: We recommend to develop clear clinical criteria for PF OA and to reach consensus on the definition of PF OA by both radiographs and MRI. Additionally, more understanding is necessary to be able to distinguish PF symptoms from those arising from the tibiofemoral joint. More insight is needed on effective treatment strategies for PF OA; specifically, tailoring nonpharmacological treatments to individuals with PF OA, and determining whether isolated PF OA requires different treatment strategies than combined PF and tibiofemoral OA.
OBJECTIVE: To present the current status of knowledge in the field of patellofemoral (PF) osteoarthritis (OA) and formulate a research agenda in order to guide future research on this topic. DESIGN: A 1-day meeting was organized with the aim to bring together international experts in the field to discuss the current state of knowledge on PF OA. Experts from multiple disciplines were invited based on their scientific publications in the field of PF OA and interest in the subject. Topics discussed include the diagnosis, impact, prognosis, and treatment of PF OA. METHODS: Following context-setting presentations, an interactive discussion was held in order to achieve consensus on the PF OA topics of interest: (1) diagnosis and definition; (2) burden; (3) outcome measures; (4) prognosis; (5) risk factors, and (6) treatment. Groups of meeting attendees reviewed the literature on these topics and narratively summarized the current state of knowledge, and each group formulated research agenda items relevant to the specific topics of interest. Each consortium member consequently ranked the importance of all items on a 0-10 Numerical Rating Scale (NRS) (10 = extremely important, to 0 = not at all important). RESULTS: After ranking all formulated items on importance, 6 of the 28 research agenda items formulated received an average of 7.5 points on the NRS. The most highly ranked items covered the fields of treatment, diagnosis, and definition of PF OA. CONCLUSIONS: We recommend to develop clear clinical criteria for PF OA and to reach consensus on the definition of PF OA by both radiographs and MRI. Additionally, more understanding is necessary to be able to distinguish PF symptoms from those arising from the tibiofemoral joint. More insight is needed on effective treatment strategies for PF OA; specifically, tailoring nonpharmacological treatments to individuals with PF OA, and determining whether isolated PF OA requires different treatment strategies than combined PF and tibiofemoral OA.
Authors: E M Macri; D T Felson; M L Ziegler; T D V Cooke; A Guermazi; F W Roemer; T Neogi; J Torner; C E Lewis; M C Nevitt; J J Stefanik Journal: Osteoarthritis Cartilage Date: 2018-11-28 Impact factor: 6.576
Authors: Central South University National Clinical Research Center For Geriatric Disorders Xiangya Hospital Journal: Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi Date: 2021-01-15
Authors: Natalie J Collins; Tuhina Neogi; Bill Vicenzino; Ali Guermazi; Frank W Roemer; Cora E Lewis; James C Torner; Michael C Nevitt; Joshua J Stefanik Journal: J Rheumatol Date: 2020-03-01 Impact factor: 4.666
Authors: Natalie J Collins; Jade M Tan; Hylton B Menz; Trevor G Russell; Anne J Smith; Bill Vicenzino; Shannon E Munteanu; Rana S Hinman; Terry P Haines; Harvi F Hart; Brooke E Patterson; Gearoid Cleary; Joel W Donnar; Liam R Maclachlan; Kay M Crossley Journal: BMJ Open Date: 2019-04-20 Impact factor: 2.692
Authors: Erin M Macri; Agnes G d'Entremont; Kay M Crossley; Harvi F Hart; Bruce B Forster; David R Wilson; Charles R Ratzlaff; Charlie H Goldsmith; Karim M Khan Journal: J Orthop Res Date: 2019-03-01 Impact factor: 3.494
Authors: J F A Eijkenboom; J H Waarsing; E H G Oei; S M A Bierma-Zeinstra; M van Middelkoop Journal: Bone Joint Res Date: 2018-10-03 Impact factor: 5.853
Authors: Jade M Tan; Kay M Crossley; Shannon E Munteanu; Natalie J Collins; Harvi F Hart; Joel W Donnar; Gearoid Cleary; Isobel C O'Sullivan; Liam R Maclachlan; Catherine L Derham; Hylton B Menz Journal: J Foot Ankle Res Date: 2020-09-23 Impact factor: 2.303
Authors: Qiuke Wang; Jos Runhaar; Margreet Kloppenburg; Maarten Boers; Johannes W J Bijlsma; Sita M A Bierma-Zeinstra Journal: J Clin Med Date: 2020-10-21 Impact factor: 4.241