Olivia A Skrobot1, Sandra E Black2, Christopher Chen3, Charles DeCarli4, Timo Erkinjuntti5, Gary A Ford6, Rajesh N Kalaria7, John O'Brien8, Leonardo Pantoni9, Florence Pasquier10, Gustavo C Roman11, Anders Wallin12, Perminder Sachdev13, Ingmar Skoog14, Yoav Ben-Shlomo15, Anthony P Passmore16, Seth Love1, Patrick G Kehoe17. 1. Translational Health Sciences, University of Bristol, Bristol, UK. 2. Sunnybrook Research Institute, University of Toronto, Ontario, Canada. 3. Department of Pharmacology, National University of Singapore, Singapore. 4. Department of Neurology and Center for Neuroscience, University of California at Davis, Sacramento, California, USA. 5. Neurology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. 6. Divison of Medical Sciences, Oxford University, Oxford, UK. 7. Institute of Neuroscience, Newcastle University, Newcastle, UK. 8. Department of Psychiatry, University of Cambridge School of Clinical Medicine, Cambridge, UK. 9. NEUROFARBA Department, University of Florence, Florence, Italy. 10. Inserm U1171, University of Lille, Lille, France. 11. Methodist Neurological Institute, Houston, Texas, USA. 12. Memory Clinic at Department of Neuropsychiatry, Sahlgrenska University Hospital, Mölndal, Sweden; Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden. 13. School of Psychiatry, University of New South Wales, Sydney, Australia; Neuropsychiatric Institute, Prince of Wales Hospital, Randwick, New South Wales, Australia. 14. Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Sweden. 15. Population Health Sciences, University of Bristol, Bristol, UK. 16. Institute of Clinical Sciences, Block B, Queens University Belfast, Belfast, UK. 17. Translational Health Sciences, University of Bristol, Bristol, UK. Electronic address: patrick.kehoe@bristol.ac.uk.
Abstract
INTRODUCTION: Progress in understanding and management of vascular cognitive impairment (VCI) has been hampered by lack of consensus on diagnosis, reflecting the use of multiple different assessment protocols. A large multinational group of clinicians and researchers participated in a two-phase Vascular Impairment of Cognition Classification Consensus Study (VICCCS) to agree on principles (VICCCS-1) and protocols (VICCCS-2) for diagnosis of VCI. We present VICCCS-2. METHODS: We used VICCCS-1 principles and published diagnostic guidelines as points of reference for an online Delphi survey aimed at achieving consensus on clinical diagnosis of VCI. RESULTS: Six survey rounds comprising 65-79 participants agreed guidelines for diagnosis of VICCCS-revised mild and major forms of VCI and endorsed the National Institute of Neurological Disorders-Canadian Stroke Network neuropsychological assessment protocols and recommendations for imaging. DISCUSSION: The VICCCS-2 suggests standardized use of the National Institute of Neurological Disorders-Canadian Stroke Network recommendations on neuropsychological and imaging assessment for diagnosis of VCI so as to promote research collaboration.
INTRODUCTION: Progress in understanding and management of vascular cognitive impairment (VCI) has been hampered by lack of consensus on diagnosis, reflecting the use of multiple different assessment protocols. A large multinational group of clinicians and researchers participated in a two-phase Vascular Impairment of Cognition Classification Consensus Study (VICCCS) to agree on principles (VICCCS-1) and protocols (VICCCS-2) for diagnosis of VCI. We present VICCCS-2. METHODS: We used VICCCS-1 principles and published diagnostic guidelines as points of reference for an online Delphi survey aimed at achieving consensus on clinical diagnosis of VCI. RESULTS: Six survey rounds comprising 65-79 participants agreed guidelines for diagnosis of VICCCS-revised mild and major forms of VCI and endorsed the National Institute of Neurological Disorders-Canadian Stroke Network neuropsychological assessment protocols and recommendations for imaging. DISCUSSION: The VICCCS-2 suggests standardized use of the National Institute of Neurological Disorders-Canadian Stroke Network recommendations on neuropsychological and imaging assessment for diagnosis of VCI so as to promote research collaboration.
Authors: Yat-Fung Shea; Warren Barker; Maria T Greig-Gusto; David A Loewenstein; Steven T DeKosky; Ranjan Duara Journal: J Alzheimers Dis Date: 2018 Impact factor: 4.472
Authors: Costantino Iadecola; Marco Duering; Vladimir Hachinski; Anne Joutel; Sarah T Pendlebury; Julie A Schneider; Martin Dichgans Journal: J Am Coll Cardiol Date: 2019-07-02 Impact factor: 24.094