Literature DB >> 29054034

An exploration of common dopaminergic variants and behavior problems in siblings at high risk for autism spectrum disorder.

Devon N Gangi1, Lauren V Usher2, Daniel S Messinger3.   

Abstract

Younger siblings of children with ASD often exhibit elevated internalizing and externalizing problems. We investigated common dopaminergic variants (DRD4 and DRD2) in relation to behavior problems at 36 months. Genotypes linked to less efficient dopaminergic functioning were associated with higher internalizing problems in high-risk siblings.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Behavior problems; Dopamine; High-risk siblings

Mesh:

Substances:

Year:  2017        PMID: 29054034      PMCID: PMC5716906          DOI: 10.1016/j.infbeh.2017.10.002

Source DB:  PubMed          Journal:  Infant Behav Dev        ISSN: 0163-6383


  31 in total

1.  A comparison of behavioral and emotional functioning in children and adolescents with Autistic Disorder and PDD-NOS.

Authors:  Deborah A Pearson; Katherine A Loveland; David Lachar; David M Lane; Stacy L Reddoch; Rosleen Mansour; Lynne A Cleveland
Journal:  Child Neuropsychol       Date:  2006-08       Impact factor: 2.500

2.  Emotional and behavioural problems in children with autism spectrum disorder.

Authors:  Morag Maskey; Frances Warnell; Jeremy R Parr; Ann Le Couteur; Helen McConachie
Journal:  J Autism Dev Disord       Date:  2013-04

3.  Risk and protective factors affecting the adjustment of siblings of children with chronic disabilities.

Authors:  S Fisman; L Wolf; D Ellison; B Gillis; T Freeman; P Szatmari
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  1996-11       Impact factor: 8.829

4.  Behavior and sleep problems in children with a family history of autism.

Authors:  Amy Jo Schwichtenberg; Gregory S Young; Ted Hutman; Ana-Maria Iosif; Marian Sigman; Sally J Rogers; Sally Ozonoff
Journal:  Autism Res       Date:  2013-02-21       Impact factor: 5.216

5.  Polygenic inheritance of Tourette syndrome, stuttering, attention deficit hyperactivity, conduct, and oppositional defiant disorder: the additive and subtractive effect of the three dopaminergic genes--DRD2, D beta H, and DAT1.

Authors:  D E Comings; S Wu; C Chiu; R H Ring; R Gade; C Ahn; J P MacMurray; G Dietz; D Muhleman
Journal:  Am J Med Genet       Date:  1996-05-31

6.  Externalizing and internalizing behaviors in ASD.

Authors:  Nirit Bauminger; Marjorie Solomon; Sally J Rogers
Journal:  Autism Res       Date:  2010-06       Impact factor: 5.216

7.  Association of DRD4 polymorphism with severity of oppositional defiant disorder, separation anxiety disorder and repetitive behaviors in children with autism spectrum disorder.

Authors:  Kenneth D Gadow; Carla J Devincent; Doreen M Olvet; Victoria Pisarevskaya; Eli Hatchwell
Journal:  Eur J Neurosci       Date:  2010-08-22       Impact factor: 3.386

8.  Genes in the dopaminergic system and delinquent behaviors across the life course: the role of social controls and risks.

Authors:  Jason D Boardman; Scott Menard; Michael E Roettger; Kelly E Knight; Brian B Boutwell; Andrew Smolen
Journal:  Crim Justice Behav       Date:  2014-06

Review 9.  Genetic and environmental influences on psychiatric comorbidity: a systematic review.

Authors:  M Cerdá; A Sagdeo; J Johnson; S Galea
Journal:  J Affect Disord       Date:  2009-12-11       Impact factor: 4.839

10.  Genetic variants of neurotransmitter-related genes and miRNAs in Egyptian autistic patients.

Authors:  Ahmed M Salem; Samira Ismail; Waheba A Zarouk; Olwya Abdul Baky; Ahmed A Sayed; Sawsan Abd El-Hamid; Sohair Salem
Journal:  ScientificWorldJournal       Date:  2013-12-23
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