Literature DB >> 29053966

Transforming Lipoxygenases: PE-Specific Enzymes in Disguise.

Ling F Ye1, Brent R Stockwell2.   

Abstract

In this issue of Cell, Wenzel et al. solve a long-standing mystery regarding how damage to cell membranes occurs during ferroptosis, an iron-dependent form of regulated cell death. They found that lipoxygenases are like Transformer toys, being converted from one enzyme type to another in the presence of the protein PEBP1.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Mesh：

Substances：

Year:  2017        PMID： 29053966      PMCID： PMC5960801          DOI： 10.1016/j.cell.2017.10.006

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  10 in total

Review 1.  Lipoxygenase and leukotriene pathways: biochemistry, biology, and roles in disease.

Authors:  Jesper Z Haeggström; Colin D Funk
Journal:  Chem Rev       Date:  2011-09-22       Impact factor: 60.622

2.  Inhibition of neuronal ferroptosis protects hemorrhagic brain.

Authors:  Qian Li; Xiaoning Han; Xi Lan; Yufeng Gao; Jieru Wan; Frederick Durham; Tian Cheng; Jie Yang; Zhongyu Wang; Chao Jiang; Mingyao Ying; Raymond C Koehler; Brent R Stockwell; Jian Wang
Journal:  JCI Insight       Date:  2017-04-06

Review 3.  Lipid peroxidation in cell death.

Authors:  Michael M Gaschler; Brent R Stockwell
Journal:  Biochem Biophys Res Commun       Date:  2017-02-03       Impact factor: 3.575

4.  Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice.

Authors:  Jose Pedro Friedmann Angeli; Manuela Schneider; Bettina Proneth; Yulia Y Tyurina; Vladimir A Tyurin; Victoria J Hammond; Nadja Herbach; Michaela Aichler; Axel Walch; Elke Eggenhofer; Devaraj Basavarajappa; Olof Rådmark; Sho Kobayashi; Tobias Seibt; Heike Beck; Frauke Neff; Irene Esposito; Rüdiger Wanke; Heidi Förster; Olena Yefremova; Marc Heinrichmeyer; Georg W Bornkamm; Edward K Geissler; Stephen B Thomas; Brent R Stockwell; Valerie B O'Donnell; Valerian E Kagan; Joel A Schick; Marcus Conrad
Journal:  Nat Cell Biol       Date:  2014-11-17       Impact factor: 28.824

5.  PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals.

Authors:  Sally E Wenzel; Yulia Y Tyurina; Jinming Zhao; Claudette M St Croix; Haider H Dar; Gaowei Mao; Vladimir A Tyurin; Tamil S Anthonymuthu; Alexandr A Kapralov; Andrew A Amoscato; Karolina Mikulska-Ruminska; Indira H Shrivastava; Elizabeth M Kenny; Qin Yang; Joel C Rosenbaum; Louis J Sparvero; David R Emlet; Xiaoyan Wen; Yoshinori Minami; Feng Qu; Simon C Watkins; Theodore R Holman; Andrew P VanDemark; John A Kellum; Ivet Bahar; Hülya Bayır; Valerian E Kagan
Journal:  Cell       Date:  2017-10-19       Impact factor: 41.582

6.  Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis.

Authors:  Valerian E Kagan; Gaowei Mao; Feng Qu; Jose Pedro Friedmann Angeli; Sebastian Doll; Claudette St Croix; Haider Hussain Dar; Bing Liu; Vladimir A Tyurin; Vladimir B Ritov; Alexandr A Kapralov; Andrew A Amoscato; Jianfei Jiang; Tamil Anthonymuthu; Dariush Mohammadyani; Qin Yang; Bettina Proneth; Judith Klein-Seetharaman; Simon Watkins; Ivet Bahar; Joel Greenberger; Rama K Mallampalli; Brent R Stockwell; Yulia Y Tyurina; Marcus Conrad; Hülya Bayır
Journal:  Nat Chem Biol       Date:  2016-11-14       Impact factor: 15.040

7.  Synchronized renal tubular cell death involves ferroptosis.

Authors:  Andreas Linkermann; Rachid Skouta; Nina Himmerkus; Shrikant R Mulay; Christin Dewitz; Federica De Zen; Agnes Prokai; Gabriele Zuchtriegel; Fritz Krombach; Patrick-Simon Welz; Ricardo Weinlich; Tom Vanden Berghe; Peter Vandenabeele; Manolis Pasparakis; Markus Bleich; Joel M Weinberg; Christoph A Reichel; Jan Hinrich Bräsen; Ulrich Kunzendorf; Hans-Joachim Anders; Brent R Stockwell; Douglas R Green; Stefan Krautwald
Journal:  Proc Natl Acad Sci U S A       Date:  2014-11-10       Impact factor: 11.205

Review 8.  Lipid homeostasis and regulated cell death.

Authors:  Eran Agmon; Brent R Stockwell
Journal:  Curr Opin Chem Biol       Date:  2017-06-20       Impact factor: 8.822

Review 9.  Ferroptosis: Death by Lipid Peroxidation.

Authors:  Wan Seok Yang; Brent R Stockwell
Journal:  Trends Cell Biol       Date:  2015-12-02       Impact factor: 20.808

10.  Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis.

Authors:  Wan Seok Yang; Katherine J Kim; Michael M Gaschler; Milesh Patel; Mikhail S Shchepinov; Brent R Stockwell
Journal:  Proc Natl Acad Sci U S A       Date:  2016-08-09       Impact factor: 11.205
  10 in total
  4 in total

1.  Evaluation of vatiquinone drug-drug interaction potential in vitro and in a phase 1 clinical study with tolbutamide, a CYP2C9 substrate, and omeprazole, a CYP2C19 substrate, in healthy subjects.

Authors:  Katsuyuki Murase; Lucy Lee; Jiyuan Ma; Rosemary Barrett; Martin Thoolen
Journal:  Eur J Clin Pharmacol       Date:  2022-09-27       Impact factor: 3.064

Review 2.  The Chemistry and Biology of Ferroptosis.

Authors:  Brent R Stockwell; Xuejun Jiang
Journal:  Cell Chem Biol       Date:  2020-04-16       Impact factor: 8.116

3.  Insight into the mechanism of ferroptosis inhibition by ferrostatin-1.

Authors:  Giovanni Miotto; Monica Rossetto; Maria Luisa Di Paolo; Laura Orian; Rina Venerando; Antonella Roveri; Ana-Marija Vučković; Valentina Bosello Travain; Mattia Zaccarin; Lucio Zennaro; Matilde Maiorino; Stefano Toppo; Fulvio Ursini; Giorgio Cozza
Journal:  Redox Biol       Date:  2019-09-20       Impact factor: 11.799

4.  Dihydroartemisinin Induces Ferroptosis in HCC by Promoting the Formation of PEBP1/15-LO.

Authors:  Ying Su; Danli Zhao; Chun Jin; Zhanghao Li; Sumin Sun; Siwei Xia; Yuxin Zhang; Zili Zhang; Feng Zhang; Xuefen Xu; Jiangjuan Shao; Biyun Zhang; Shizhong Zheng
Journal:  Oxid Med Cell Longev       Date:  2021-12-10       Impact factor: 6.543
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.