Literature DB >> 29053948

Nanoscale Imaging Reveals Big Role for Iron in Alzheimer's Disease.

Scott Ayton1, Simon A James1, Ashley I Bush2.   

Abstract

In this issue of Cell Chemical Biology, Telling et al. (2017) apply advanced X-ray microscopy techniques to reveal magnetite iron species in plaques from a mouse model of Alzheimer's disease. The characterization of abnormal iron chemistry in the disease model highlights the potential for iron to combine with the β-amyloid peptide and accelerate the disease process.
Copyright © 2017 Elsevier Ltd. All rights reserved.

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Year:  2017        PMID: 29053948     DOI: 10.1016/j.chembiol.2017.10.002

Source DB:  PubMed          Journal:  Cell Chem Biol        ISSN: 2451-9448            Impact factor:   8.116


  4 in total

Review 1.  Treating Alzheimer's disease by targeting iron.

Authors:  Sara Nikseresht; Ashley I Bush; Scott Ayton
Journal:  Br J Pharmacol       Date:  2019-02-11       Impact factor: 8.739

Review 2.  No effects without causes: the Iron Dysregulation and Dormant Microbes hypothesis for chronic, inflammatory diseases.

Authors:  Douglas B Kell; Etheresia Pretorius
Journal:  Biol Rev Camb Philos Soc       Date:  2018-03-25

3.  Brain iron is associated with accelerated cognitive decline in people with Alzheimer pathology.

Authors:  Martha Clare Morris; Ashley I Bush; Scott Ayton; Yamin Wang; Ibrahima Diouf; Julie A Schneider; John Brockman
Journal:  Mol Psychiatry       Date:  2019-02-18       Impact factor: 15.992

Review 4.  Iron and Alzheimer's Disease: From Pathogenesis to Therapeutic Implications.

Authors:  Jun-Lin Liu; Yong-Gang Fan; Zheng-Sheng Yang; Zhan-You Wang; Chuang Guo
Journal:  Front Neurosci       Date:  2018-09-10       Impact factor: 4.677

  4 in total

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