Literature DB >> 2905345

Population genetics of the globin genes in Polynesians.

R J Trent1, K N Mickleson, J Yakas, M Hertzberg.   

Abstract

Globin gene mapping data enable Polynesians to be divided into three distinct groups: (i) Maoris, Cook Islanders, (ii) Tongans, Samoans, (iii) Niue Islanders. Unusual RFLPs detected by the restriction enzymes Apa I and Bgl II are found in Polynesians. A high frequency of alpha-thalassemia in this population is explained by genetic drift and a founder effect.

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Year:  1988        PMID: 2905345     DOI: 10.3109/03630268808991642

Source DB:  PubMed          Journal:  Hemoglobin        ISSN: 0363-0269            Impact factor:   0.849


  2 in total

1.  Diagnosis of the haemoglobinopathies.

Authors:  Ronald J A Trent
Journal:  Clin Biochem Rev       Date:  2006-02

2.  The SLC2A9 nonsynonymous Arg265His variant and gout: evidence for a population-specific effect on severity.

Authors:  Jade E Hollis-Moffatt; Peter J Gow; Andrew A Harrison; John Highton; Peter B B Jones; Lisa K Stamp; Nicola Dalbeth; Tony R Merriman
Journal:  Arthritis Res Ther       Date:  2011-06-09       Impact factor: 5.156

  2 in total

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