Circadian rhythms in adaptation to light of Limulus photoreception.

1. The lateral eye of Limulus responds differently to light-adaptation depending upon whether the eye is tested during the day, or at night when a central circadian clock is known to activate efferent fibers that terminate in the retina. 2. At night, the decrement in retinal sensitivity due to light-adaptation is less pronounced immediately following a light-flash but is greater at longer times after the flash when compared with responses recorded during the day. 3. In our quantitative description of dark adaptation we find that at least two time constants are needed to describe the time course, and that the two decaying exponentials are differentially altered by circadian clock action. 4. We relate these day-to-night alterations in light-adaptive properties to circadian changes in physiology and morphology studied previously in Limulus photoreceptors.