Literature DB >> 29052134

Kaposi's Sarcoma-Associated Herpesvirus: Epidemiology and Molecular Biology.

Shasha Li1, Lei Bai2, Jiazhen Dong2, Rui Sun2, Ke Lan3.   

Abstract

Kaposi's sarcoma-associated herpesvirus (KSHV), also known as Human herpesvirus 8 (HHV-8), is a member of the lymphotropic gammaherpesvirus subfamily and a human oncogenic virus. Since its discovery in AIDS-associated KS tissues by Drs. Yuan Chang and Patrick Moore, much progress has been made in the past two decades. There are four types of KS including classic KS, endemic KS, immunosuppressive therapy-related KS, and AIDS-associated KS. In addition to KS, KSHV is also involved in the development of primary effusion lymphoma (PEL) and certain types of multicentric Castleman's disease. KSHV manipulates numerous viral proteins to promote the progression of angiogenesis and tumorigenesis. In this chapter, we review the epidemiology and molecular biology of KSHV and the mechanisms underlying KSHV-induced diseases.

Entities:  

Keywords:  KSHV epidemiology; KSHV life cycle; KSHV pathogenesis; Kaposi’s sarcoma-associated herpesvirus

Mesh：

Year:  2017        PMID： 29052134     DOI： 10.1007/978-981-10-5765-6_7

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN： 0065-2598            Impact factor:   2.622


  9 in total

1.  Kaposi Sarcoma of the Medial Foot in an MSM, HIV-Negative Man: A Fifth Clinical Variant.

Authors:  Ritu Swali; Allison Limmer; Stephen K Tyring
Journal:  J Clin Aesthet Dermatol       Date:  2020-10-01

2.  Antiretroviral Therapy for HIV-Associated Cutaneous Kaposi's Sarcoma: Clinical, HIV-Related, and Sociodemographic Predictors of Outcome.

Authors:  Owen Ngalamika; Sody Munsaka; Salum J Lidenge; John T West; Charles Wood
Journal:  AIDS Res Hum Retroviruses       Date:  2021-02-02       Impact factor: 2.205

Review 3.  Viral hijacking of cellular metabolism.

Authors:  Shivani K Thaker; James Ch'ng; Heather R Christofk
Journal:  BMC Biol       Date:  2019-07-18       Impact factor: 7.431

4.  Bioinformatics analysis of key biomarkers and pathways in KSHV infected endothelial cells.

Authors:  Hai-Bo Gong; Xiu-Juan Wu; Xiong-Ming Pu; Xiao-Jing Kang
Journal:  Medicine (Baltimore)       Date:  2019-07       Impact factor: 1.817

5.  Molecular basis of EphA2 recognition by gHgL from gammaherpesviruses.

Authors:  Chao Su; Lili Wu; Yan Chai; Jianxun Qi; Shuguang Tan; George F Gao; Hao Song; Jinghua Yan
Journal:  Nat Commun       Date:  2020-11-24       Impact factor: 14.919

6.  Primary effusion lymphoma in a patient with a good outcome on steroid alone treatment.

Authors:  Ofir Koren; Ariel Aviv; Moran Avraham Kelbert; Ehud Rozner; Liza Lihtman; Elya Halfin; Yoav Turgeman
Journal:  Clin Case Rep       Date:  2021-03-04

Review 7.  Berberine in Human Oncogenic Herpesvirus Infections and Their Linked Cancers.

Authors:  Miroslava Šudomová; Kateřina Berchová-Bímová; Stefania Marzocco; Alena Liskova; Peter Kubatka; Sherif T S Hassan
Journal:  Viruses       Date:  2021-05-28       Impact factor: 5.048

Review 8.  The Critical Role of Genome Maintenance Proteins in Immune Evasion During Gammaherpesvirus Latency.

Authors:  Océane Sorel; Benjamin G Dewals
Journal:  Front Microbiol       Date:  2019-01-09       Impact factor: 5.640

Review 9.  Flavonoids Target Human Herpesviruses That Infect the Nervous System: Mechanisms of Action and Therapeutic Insights.

Authors:  Miroslava Šudomová; Kateřina Berchová-Bímová; Alena Mazurakova; Dunja Šamec; Peter Kubatka; Sherif T S Hassan
Journal:  Viruses       Date:  2022-03-13       Impact factor: 5.048
  9 in total

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