Literature DB >> 29051945

Cancer classification with a network of chemical oscillators.

Konrad Gizynski1, Jerzy Gorecki.   

Abstract

We discuss chemical information processing considering dataset classifiers formed with a network of interacting droplets. Our arguments are based on computer simulations of droplets in which a photosensitive variant of the Belousov-Zhabotinsky (BZ) reaction proceeds. By applying optical control we can adjust the time evolution of individual droplets and prepare the network to perform a specific computational task. We demonstrate that chemical classifiers made of droplets can be designed in computer simulations based on evolutionary algorithms. The mutual information between the dataset and the observed time evolution of droplets in the network is taken as the fitness function in the optimization process. We show that a classifier of the Wisconsin Breast Cancer Dataset made of a relatively small number of droplets can distinguish between malignant and benign forms of cancer with an accuracy exceeding 97%. The reliability of the optimized chemical classifiers of this dataset as a function of optimization time, number of droplets involved in data processing and the method of extracting the output information is discussed.

Entities:  

Year:  2017        PMID: 29051945     DOI: 10.1039/c7cp05655a

Source DB:  PubMed          Journal:  Phys Chem Chem Phys        ISSN: 1463-9076            Impact factor:   3.676


  4 in total

1.  Applications of Information Theory Methods for Evolutionary Optimization of Chemical Computers.

Authors:  Jerzy Gorecki
Journal:  Entropy (Basel)       Date:  2020-03-10       Impact factor: 2.524

2.  Computing With Networks of Chemical Oscillators and its Application for Schizophrenia Diagnosis.

Authors:  Ashmita Bose; Jerzy Gorecki
Journal:  Front Chem       Date:  2022-02-16       Impact factor: 5.221

3.  The Concilium of Information Processing Networks of Chemical Oscillators for Determining Drug Response in Patients With Multiple Myeloma.

Authors:  Ashmita Bose; Peter Dittrich; Jerzy Gorecki
Journal:  Front Chem       Date:  2022-07-08       Impact factor: 5.545

4.  Information Processing Using Networks of Chemical Oscillators.

Authors:  Jerzy Gorecki
Journal:  Entropy (Basel)       Date:  2022-07-31       Impact factor: 2.738

  4 in total

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