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Literature DB >> 29051142

APOL1 and Proteinuria in the AASK: Unraveling the Pathobiology of APOL1.

John F O'Toole^1,2, Leslie A Bruggeman^1,2, John R Sedor^3,4.

Abstract

Entities: Chemical

Keywords: AASK (African American Study of Kidney Disease and Hypertension); APOL1; Apolipoprotein L1; Apolipoproteins; podocyte; precision medicine; proteinuria

Mesh：

Substances：

Year: 2017 PMID： 29051142 PMCID： PMC5672982 DOI： 10.2215/CJN.10680917

Source DB: PubMed Journal: Clin J Am Soc Nephrol ISSN： 1555-9041 Impact factor: 10.614

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16 in total

1. Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice.

Authors: Pazit Beckerman; Jing Bi-Karchin; Ae Seo Deok Park; Chengxiang Qiu; Patrick D Dummer; Irfana Soomro; Carine M Boustany-Kari; Steven S Pullen; Jeffrey H Miner; Chien-An A Hu; Tibor Rohacs; Kazunori Inoue; Shuta Ishibe; Moin A Saleem; Matthew B Palmer; Ana Maria Cuervo; Jeffrey B Kopp; Katalin Susztak
Journal: Nat Med Date: 2017-02-20 Impact factor: 53.440

2. A tripartite complex of suPAR, APOL1 risk variants and α_vβ₃ integrin on podocytes mediates chronic kidney disease.

Authors: Salim S Hayek; Kwi Hye Koh; Morgan E Grams; Changli Wei; Yi-An Ko; Jing Li; Beata Samelko; Hyun Lee; Ranadheer R Dande; Ha Won Lee; Eunsil Hahm; Vasil Peev; Melissa Tracy; Nicholas J Tardi; Vineet Gupta; Mehmet M Altintas; Garrett Garborcauskas; Nikolina Stojanovic; Cheryl A Winkler; Michael S Lipkowitz; Adrienne Tin; Lesley A Inker; Andrew S Levey; Martin Zeier; Barry I Freedman; Jeffrey B Kopp; Karl Skorecki; Josef Coresh; Arshed A Quyyumi; Sanja Sever; Jochen Reiser
Journal: Nat Med Date: 2017-06-26 Impact factor: 53.440

3. Estimating time to ESRD using kidney failure risk equations: results from the African American Study of Kidney Disease and Hypertension (AASK).

Authors: Morgan E Grams; Liang Li; Tom H Greene; Adrienne Tin; Yingying Sang; W H Linda Kao; Michael S Lipkowitz; Jackson T Wright; Alex R Chang; Brad C Astor; Lawrence J Appel
Journal: Am J Kidney Dis Date: 2014-10-14 Impact factor: 8.860

4. APOL1-Mediated Cell Injury Involves Disruption of Conserved Trafficking Processes.

Authors: Etty Kruzel-Davila; Revital Shemer; Ayala Ofir; Ira Bavli-Kertselli; Ilona Darlyuk-Saadon; Pazit Oren-Giladi; Walter G Wasser; Daniella Magen; Eid Zaknoun; Maya Schuldiner; Adi Salzberg; Daniel Kornitzer; Zvonimir Marelja; Matias Simons; Karl Skorecki
Journal: J Am Soc Nephrol Date: 2016-11-18 Impact factor: 10.121

APOL1 and Proteinuria in the AASK: Unraveling the Pathobiology of APOL1.

1. Transgenic expression of human APOL1 risk variants in podocytes induces kidney disease in mice.

2. A tripartite complex of suPAR, APOL1 risk variants and α_vβ₃ integrin on podocytes mediates chronic kidney disease.

3. Estimating time to ESRD using kidney failure risk equations: results from the African American Study of Kidney Disease and Hypertension (AASK).

4. APOL1-Mediated Cell Injury Involves Disruption of Conserved Trafficking Processes.

Review 5. Podometrics as a Potential Clinical Tool for Glomerular Disease Management.

6. From man to fish: What can Zebrafish tell us about ApoL1 nephropathy?

Review 7. Apolipoprotein L1 and Kidney Disease in African Americans.

8. APOL1-G0 or APOL1-G2 Transgenic Models Develop Preeclampsia but Not Kidney Disease.

9. APOL1 Risk Variants, Incident Proteinuria, and Subsequent eGFR Decline in Blacks with Hypertension-Attributed CKD.

10. Glomerular permeability. I. Ferritin transfer across the normal glomerular capillary wall.

Review 1. Pharmacotherapeutic options for kidney disease in HIV positive patients.