PURPOSE OF REVIEW: Atrial fibrillation may be detected in the setting of an acute stressor, such as medical illness or surgery. It is uncertain if atrial fibrillation detected in these settings (AFOTS: atrial fibrillation occurring transiently with stress) is secondary to a reversible trigger or is simply paroxysmal atrial fibrillation. This distinction is critical for clinicians, who must decide if AFOTS can be dismissed as a reversible phenomenon, or if it signals the need for chronic therapy; in particular, anticoagulation. RECENT FINDINGS: Published studies report incidences of AFOTS ranging from 1 to 44% in patients with acute medical illness and 1 to 35% following noncardiac surgery. The highest estimates have been reported in critically ill patients and in those undergoing continuous monitoring. A small number of studies have reported the recurrence of atrial fibrillation after AFOTS to be 55-68% within 5 years of medical illness and 37% within 1 year after noncardiac surgery. These studies are limited by retrospective design and low-sensitivity ascertainment. SUMMARY: AFOTS commonly occurs in patients with acute medical illness or in the postoperative state, and atrial fibrillation recurs in over 50% of individuals. Prospective postdischarge studies using sensitive atrial fibrillation detection strategies are needed to define the relationship between AFOTS and clinical atrial fibrillation.
PURPOSE OF REVIEW: Atrial fibrillation may be detected in the setting of an acute stressor, such as medical illness or surgery. It is uncertain if atrial fibrillation detected in these settings (AFOTS: atrial fibrillation occurring transiently with stress) is secondary to a reversible trigger or is simply paroxysmal atrial fibrillation. This distinction is critical for clinicians, who must decide if AFOTS can be dismissed as a reversible phenomenon, or if it signals the need for chronic therapy; in particular, anticoagulation. RECENT FINDINGS: Published studies report incidences of AFOTS ranging from 1 to 44% in patients with acute medical illness and 1 to 35% following noncardiac surgery. The highest estimates have been reported in critically illpatients and in those undergoing continuous monitoring. A small number of studies have reported the recurrence of atrial fibrillation after AFOTS to be 55-68% within 5 years of medical illness and 37% within 1 year after noncardiac surgery. These studies are limited by retrospective design and low-sensitivity ascertainment. SUMMARY: AFOTS commonly occurs in patients with acute medical illness or in the postoperative state, and atrial fibrillation recurs in over 50% of individuals. Prospective postdischarge studies using sensitive atrial fibrillation detection strategies are needed to define the relationship between AFOTS and clinical atrial fibrillation.
Authors: William F McIntyre; Pablo A Mendoza; Emilie P Belley-Côté; Richard P Whitlock; Kevin J Um; Natalie Maystrenko; P J Devereaux; David Conen; Jorge A Wong; Stuart J Connolly; Jeff S Healey Journal: Clin Cardiol Date: 2018-10-18 Impact factor: 2.882
Authors: William F McIntyre; Kevin J Um; Waleed Alhazzani; Alexandra P Lengyel; Ludhmila Hajjar; Anthony C Gordon; François Lamontagne; Jeff S Healey; Richard P Whitlock; Emilie P Belley-Côté Journal: JAMA Date: 2018-05-08 Impact factor: 56.272
Authors: William F McIntyre; Emilie P Belley-Côté; Maria E Vadakken; Anand S Rai; Alexandra P Lengyel; Bram Rochwerg; Akash K Bhatnagar; Bishoy Deif; Kevin J Um; Jessica Spence; Stuart J Connolly; Shrikant I Bangdiwala; Purnima Rao-Melacini; Jeff S Healey; Richard P Whitlock Journal: Crit Care Explor Date: 2021-01-08
Authors: Jessica T Huynh; Jeff S Healey; Kevin J Um; Maria E Vadakken; Anand S Rai; David Conen; Pascal Meyre; Jawad H Butt; Hooman Kamel; Seleman J Reza; Stephanie T Nguyen; Zardasht Oqab; P J Devereaux; Kumar Balasubramanian; Alexander P Benz; Emilie P Belley-Cote; William F McIntyre Journal: CJC Open Date: 2021-01-12