| Literature DB >> 2904859 |
M Peral de Bruno1, P Lebenshon de Chialvo, A Coviello.
Abstract
1. The vascular response to Asn1-Val5 angiotensin II (A II) in aortic rings from Bufo arenarum toad was studied. 2. Tachyphylaxis in response to A II could be abolished after incubation with norepinephrine (NE). 3. Phentolamine treatment partially inhibited the pressor effects to A II. 4. Sar1-Ile8 A II and Sar1-Ala8 A II significantly attenuated the vascular effects of A II and did not affect the NE response. 5. We conclude that the pressor response to A II has a direct contractile effect and a catecholamine dependent component in aortic rings of Bufo arenarum toad.Entities:
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Year: 1988 PMID： 2904859 DOI： 10.1016/0742-8413(88)90119-3
Source DB: PubMed Journal: Comp Biochem Physiol C Comp Pharmacol Toxicol ISSN： 0742-8413