BACKGROUND: While T1-weighted gadolinium-enhanced (T1-Gd) magnetic resonance imaging (MRI) is the standard imaging sequence for trajectory planning of stereotactic procedures, including deep brain stimulation, stereoelectroencephalography, and laser interstitial thermal therapy, susceptibility-weighted imaging (SWI) has been reported to demonstrate increased sensitivity for the visualization of microvasculature. OBJECTIVE: To determine the impact of SWI visualization on trajectory planning for electrode implantation and evaluate the relationship between the rate of vessel-electrode intersections and intracerebral hemorrhage (ICH). METHODS: We conducted a retrospective study of 13 patients who underwent stereoelectroencephalography and laser interstitial thermal therapy placement between 2014 and 2015, using their preoperative T1-Gd and SWI scans, and postoperative MRI scans to determine the rate of vessel-electrode intersections seen on the 2 imaging modalities, the mean diameter and depth of the vessels identified, and the rate of ICH after implantation. RESULTS: Among 13 patients, 106 electrodes were implanted. Sixty-three unique vessel-electrode intersections were identified on SWI with a mean of 4.85 intersections per patient. There were 13 intersections seen on T1-Gd with a mean of 1 intersection per patient. The intersected vessels visualized on SWI had a diameter of 1.49 ± 0.46 mm and those on T1-Gd were 2.01 ± 0.52 mm. There was no clear ICH observed in this series. CONCLUSION: SWI allows for improved visualization of the smaller, deep vessels, whereas T1-Gd adequately detects superficial, larger vessels. Despite the larger number of vessel-electrode intersections seen on SWI, no clear evidence of ICH was identified. Increased detection of deep vasculature does not appear to significantly benefit trajectory planning for stereotactic intracranial procedures and may limit the number of trajectories perceived to be safe.
BACKGROUND: While T1-weighted gadolinium-enhanced (T1-Gd) magnetic resonance imaging (MRI) is the standard imaging sequence for trajectory planning of stereotactic procedures, including deep brain stimulation, stereoelectroencephalography, and laser interstitial thermal therapy, susceptibility-weighted imaging (SWI) has been reported to demonstrate increased sensitivity for the visualization of microvasculature. OBJECTIVE: To determine the impact of SWI visualization on trajectory planning for electrode implantation and evaluate the relationship between the rate of vessel-electrode intersections and intracerebral hemorrhage (ICH). METHODS: We conducted a retrospective study of 13 patients who underwent stereoelectroencephalography and laser interstitial thermal therapy placement between 2014 and 2015, using their preoperative T1-Gd and SWI scans, and postoperative MRI scans to determine the rate of vessel-electrode intersections seen on the 2 imaging modalities, the mean diameter and depth of the vessels identified, and the rate of ICH after implantation. RESULTS: Among 13 patients, 106 electrodes were implanted. Sixty-three unique vessel-electrode intersections were identified on SWI with a mean of 4.85 intersections per patient. There were 13 intersections seen on T1-Gd with a mean of 1 intersection per patient. The intersected vessels visualized on SWI had a diameter of 1.49 ± 0.46 mm and those on T1-Gd were 2.01 ± 0.52 mm. There was no clear ICH observed in this series. CONCLUSION: SWI allows for improved visualization of the smaller, deep vessels, whereas T1-Gd adequately detects superficial, larger vessels. Despite the larger number of vessel-electrode intersections seen on SWI, no clear evidence of ICH was identified. Increased detection of deep vasculature does not appear to significantly benefit trajectory planning for stereotactic intracranial procedures and may limit the number of trajectories perceived to be safe.
Authors: Vejay N Vakharia; Rachel Sparks; Sjoerd B Vos; Andrew W McEvoy; Anna Miserocchi; Sebastien Ourselin; John S Duncan Journal: World Neurosurg X Date: 2019-08-05