Gary L Pierce1,2,3. 1. Department of Health and Human Physiology, University of Iowa, 225 S. Grand Ave, 412 FH, Iowa City, IA, 52242, USA. gary-pierce@uiowa.edu. 2. UI Healthcare Center for Hypertension Research, University of Iowa, Iowa City, IA, 52242, USA. gary-pierce@uiowa.edu. 3. Abboud Cardiovascular Research Center, University of Iowa, Iowa City, IA, 52242, USA. gary-pierce@uiowa.edu.
Abstract
PURPOSE OF REVIEW: Habitual aerobic exercise is associated with lower aortic stiffness, as measured by carotid-femoral pulse wave velocity (CFPWV), in middle-aged/older adults without hypertension, but beneficial effects of aerobic exercise on CFPWV in hypertension remain contraversial. Therefore, the focus of this review is to discuss the evidence for and against the beneficial effects of aerobic exercise on aortic stiffness in middle-aged and older adults with hypertension, possible limitations in these studies, and highlight novel directions for future research. RECENT FINDINGS: Most randomized controlled intervention studies demonstrate that short-term aerobic exercise results in no reductions in CFPWV in middle-aged and/or older adults with treated or treatment-naïve hypertension. Higher aerobic fitness is not associated with lower aortic stiffness among older adults with treated hypertension. Aortic stiffness appears to be resistant to clinically relevant improvements in response to habitual aerobic exercise in the presence of hypertension among middle-aged and older adults.
PURPOSE OF REVIEW: Habitual aerobic exercise is associated with lower aortic stiffness, as measured by carotid-femoral pulse wave velocity (CFPWV), in middle-aged/older adults without hypertension, but beneficial effects of aerobic exercise on CFPWV in hypertension remain contraversial. Therefore, the focus of this review is to discuss the evidence for and against the beneficial effects of aerobic exercise on aortic stiffness in middle-aged and older adults with hypertension, possible limitations in these studies, and highlight novel directions for future research. RECENT FINDINGS: Most randomized controlled intervention studies demonstrate that short-term aerobic exercise results in no reductions in CFPWV in middle-aged and/or older adults with treated or treatment-naïve hypertension. Higher aerobic fitness is not associated with lower aortic stiffness among older adults with treated hypertension. Aortic stiffness appears to be resistant to clinically relevant improvements in response to habitual aerobic exercise in the presence of hypertension among middle-aged and older adults.
Authors: Kerrie L Moreau; Anthony J Donato; Douglas R Seals; Christopher A DeSouza; Hirofumi Tanaka Journal: Cardiovasc Res Date: 2003-03 Impact factor: 10.787
Authors: Miriam Y Cortez-Cooper; Allison E DeVan; Maria M Anton; Roger P Farrar; Kimberly A Beckwith; Janice S Todd; Hirofumi Tanaka Journal: Am J Hypertens Date: 2005-07 Impact factor: 2.689
Authors: Francesco Fantin; Andrea Rossi; Susanna Morgante; Diego Soave; Luisa Bissoli; Marco Cazzadori; Maria Elena Vivian; Massimo Valsecchi; Mauro Zamboni Journal: Hypertens Res Date: 2012-07-05 Impact factor: 3.872
Authors: Yoav Ben-Shlomo; Melissa Spears; Chris Boustred; Margaret May; Simon G Anderson; Emelia J Benjamin; Pierre Boutouyrie; James Cameron; Chen-Huan Chen; J Kennedy Cruickshank; Shih-Jen Hwang; Edward G Lakatta; Stephane Laurent; João Maldonado; Gary F Mitchell; Samer S Najjar; Anne B Newman; Mitsuru Ohishi; Bruno Pannier; Telmo Pereira; Ramachandran S Vasan; Tomoki Shokawa; Kim Sutton-Tyrell; Francis Verbeke; Kang-Ling Wang; David J Webb; Tine Willum Hansen; Sophia Zoungas; Carmel M McEniery; John R Cockcroft; Ian B Wilkinson Journal: J Am Coll Cardiol Date: 2013-11-13 Impact factor: 24.094
Authors: Daniel H Craighead; Kaitlin A Freeberg; Grace S Maurer; Valerie H Myers; Douglas R Seals Journal: Exerc Sport Sci Rev Date: 2022-03-14 Impact factor: 6.642
Authors: Mary N Woessner; Michael A Welsch; Mitch D VanBruggen; Neil M Johannsen; Daniel P Credeur; Carl F Pieper; Richard Sloane; Conrad P Earnest; Joaquin Ortiz De Zevallos Munoz; Timothy S Church; Eric Ravussin; William E Kraus; Jason D Allen Journal: J Aging Phys Act Date: 2021-08-04 Impact factor: 2.109
Authors: Francisco A Júnior; Samuel G Gomes; Fernando F da Silva; Perciliany M Souza; Emerson C Oliveira; Daniel B Coelho; Raimundo M Nascimento-Neto; Wanderson Lima; Lenice K Becker Journal: Cardiovasc J Afr Date: 2019-10-25 Impact factor: 1.167
Authors: Rachel A Gioscia-Ryan; Zachary S Clayton; Melanie C Zigler; James J Richey; Lauren M Cuevas; Matthew J Rossman; Micah L Battson; Brian P Ziemba; David A Hutton; Nicholas S VanDongen; Douglas R Seals Journal: J Physiol Date: 2020-10-28 Impact factor: 5.182
Authors: Daniel H Craighead; Thomas C Heinbockel; Kaitlin A Freeberg; Matthew J Rossman; Rachel A Jackman; Lindsey R Jankowski; Makinzie N Hamilton; Brian P Ziemba; Julie A Reisz; Angelo D'Alessandro; L Madden Brewster; Christopher A DeSouza; Zhiying You; Michel Chonchol; E Fiona Bailey; Douglas R Seals Journal: J Am Heart Assoc Date: 2021-06-29 Impact factor: 5.501