Literature DB >> 29046099

Neuroendocrine tumours within a Meckel's diverticulum.

I Mora-Guzmán1, J L Muñoz de Nova1, E Martín-Pérez1.   

Abstract

A Meckel's diverticulum is a common anomaly of the gastrointestinal tract. Although the majority of patients do not have any symptoms, malignancies can develop inside these diverticula, with neuroendocrine tumours being the most common. Diverticulectomy is the best option for complicated diverticula but prophylactic resection of asymptomatic diverticula in adults remains controversial. We present a case series of three patients with a neuroendocrine tumour found in a Meckel's diverticulum. Given the number of asymptomatic diverticula not resected, it seems likely that incidental neuroendocrine tumours are more prevalent than thought previously. With the minimally invasive techniques now available and the low complication rate for incidental diverticulectomy, we believe that the benefits of resection of this high risk area for cancer outweigh the risks of surgery.

Entities:  

Keywords:  Carcinoid; Diverticulectomy; Meckel’s diverticulum; Neuroendocrine tumour

Mesh:

Year:  2017        PMID: 29046099      PMCID: PMC5838679          DOI: 10.1308/rcsbull.2018.10

Source DB:  PubMed          Journal:  Ann R Coll Surg Engl        ISSN: 0035-8843            Impact factor:   1.951


  5 in total

1.  ENETS Consensus Guidelines Update for Neuroendocrine Neoplasms of the Jejunum and Ileum.

Authors:  B Niederle; U-F Pape; F Costa; D Gross; F Kelestimur; U Knigge; K Öberg; M Pavel; A Perren; C Toumpanakis; J O'Connor; D O'Toole; E Krenning; N Reed; R Kianmanesh
Journal:  Neuroendocrinology       Date:  2016-01-12       Impact factor: 4.914

2.  Acute appendicitis and carcinoid tumor in Meckel's diverticulum. Three pathologies in one: a case report.

Authors:  N Mudatsakis; S Paraskakis; K Lasithiotakis; E Andreadakis; P Karatsis
Journal:  Tech Coloproctol       Date:  2011-10       Impact factor: 3.781

3.  Meckel's diverticulum--a high-risk region for malignancy in the ileum. Insights from a population-based epidemiological study and implications in surgical management.

Authors:  Pragatheeshwar Thirunavukarasu; Magesh Sathaiah; Shyam Sukumar; Christopher J Bartels; Herbert Zeh; Kenneth K W Lee; David L Bartlett
Journal:  Ann Surg       Date:  2011-02       Impact factor: 12.969

4.  Neuroendocrine tumors of Meckel's diverticulum: lessons from a single institution study of eight cases.

Authors:  Gilles Poncet; Valérie Hervieu; Thomas Walter; Florian Lépinasse; Laurence Chardon; Frank Pilleul; Catherine Lombard-Bohas; Jean-Alain Chayvialle; Christian Partensky; Jean-Yves Scoazec
Journal:  J Gastrointest Surg       Date:  2010-09-08       Impact factor: 3.452

5.  Neuroendocrine tumors arising in Meckel's diverticula: frequency of advanced disease warrants aggressive management.

Authors:  Allison W Lorenzen; Thomas M O'Dorisio; James R Howe
Journal:  J Gastrointest Surg       Date:  2013-04-05       Impact factor: 3.452

  5 in total
  1 in total

Review 1.  The Many Faces of Meckel's Diverticulum: Update on Management in Incidental and Symptomatic Patients.

Authors:  Robbert-Jan Lindeman; Kjetil Søreide
Journal:  Curr Gastroenterol Rep       Date:  2020-01-13
  1 in total

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