Literature DB >> 29045383

Drug discovery: Controlling protein SUMOylation.

John S Schneekloth1.   

Abstract

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Year:  2017        PMID： 29045383      PMCID： PMC6309398          DOI： 10.1038/nchembio.2496

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


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  9 in total

1.  Sumoylation by Ubc9 regulates the stem cell compartment and structure and function of the intestinal epithelium in mice.

Authors:  Maud D Demarque; Karim Nacerddine; Hélène Neyret-Kahn; Alexandra Andrieux; Esther Danenberg; Grégory Jouvion; Perrine Bomme; Ghislaine Hamard; Béatrice Romagnolo; Benoît Terris; Ana Cumano; Nick Barker; Hans Clevers; Anne Dejean
Journal:  Gastroenterology       Date:  2010-10-14       Impact factor: 22.682

Review 2.  Concepts in sumoylation: a decade on.

Authors:  Ruth Geiss-Friedlander; Frauke Melchior
Journal:  Nat Rev Mol Cell Biol       Date:  2007-12       Impact factor: 94.444

3.  Substrate-assisted inhibition of ubiquitin-like protein-activating enzymes: the NEDD8 E1 inhibitor MLN4924 forms a NEDD8-AMP mimetic in situ.

Authors:  James E Brownell; Michael D Sintchak; James M Gavin; Hua Liao; Frank J Bruzzese; Nancy J Bump; Teresa A Soucy; Michael A Milhollen; Xiaofeng Yang; Anne L Burkhardt; Jingya Ma; Huay-Keng Loke; Trupti Lingaraj; Dongyun Wu; Kristin B Hamman; James J Spelman; Courtney A Cullis; Steven P Langston; Stepan Vyskocil; Todd B Sells; William D Mallender; Irache Visiers; Ping Li; Christopher F Claiborne; Mark Rolfe; Joseph B Bolen; Lawrence R Dick
Journal:  Mol Cell       Date:  2010-01-15       Impact factor: 17.970

4.  A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis.

Authors:  Jessica D Kessler; Kristopher T Kahle; Tingting Sun; Kristen L Meerbrey; Michael R Schlabach; Earlene M Schmitt; Samuel O Skinner; Qikai Xu; Mamie Z Li; Zachary C Hartman; Mitchell Rao; Peng Yu; Rocio Dominguez-Vidana; Anthony C Liang; Nicole L Solimini; Ronald J Bernardi; Bing Yu; Tiffany Hsu; Ido Golding; Ji Luo; C Kent Osborne; Chad J Creighton; Susan G Hilsenbeck; Rachel Schiff; Chad A Shaw; Stephen J Elledge; Thomas F Westbrook
Journal:  Science       Date:  2011-12-08       Impact factor: 47.728

Review 5.  The SUMO pathway: emerging mechanisms that shape specificity, conjugation and recognition.

Authors:  Jaclyn R Gareau; Christopher D Lima
Journal:  Nat Rev Mol Cell Biol       Date:  2010-12       Impact factor: 94.444

6.  Oncogenesis driven by the Ras/Raf pathway requires the SUMO E2 ligase Ubc9.

Authors:  Bing Yu; Stephen Swatkoski; Alesia Holly; Liam C Lee; Valentin Giroux; Chih-Shia Lee; Dennis Hsu; Jordan L Smith; Garmen Yuen; Junqiu Yue; David K Ann; R Mark Simpson; Chad J Creighton; William D Figg; Marjan Gucek; Ji Luo
Journal:  Proc Natl Acad Sci U S A       Date:  2015-03-24       Impact factor: 11.205

7.  Detecting endogenous SUMO targets in mammalian cells and tissues.

Authors:  Janina Becker; Sina V Barysch; Samir Karaca; Claudia Dittner; He-Hsuan Hsiao; Mauricio Berriel Diaz; Stephan Herzig; Henning Urlaub; Frauke Melchior
Journal:  Nat Struct Mol Biol       Date:  2013-03-17       Impact factor: 15.369

8.  Probing the roles of SUMOylation in cancer cell biology by using a selective SAE inhibitor.

Authors:  Xingyue He; Jessica Riceberg; Teresa Soucy; Erik Koenig; James Minissale; Melissa Gallery; Hugues Bernard; Xiaofeng Yang; Hua Liao; Claudia Rabino; Pooja Shah; Kristina Xega; Zhong-Hua Yan; Mike Sintchak; John Bradley; He Xu; Matt Duffey; Dylan England; Hirotake Mizutani; Zhigen Hu; Jianping Guo; Ryan Chau; Lawrence R Dick; James E Brownell; John Newcomb; Steve Langston; Eric S Lightcap; Neil Bence; Sai M Pulukuri
Journal:  Nat Chem Biol       Date:  2017-09-11       Impact factor: 15.040

9.  An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer.

Authors:  Teresa A Soucy; Peter G Smith; Michael A Milhollen; Allison J Berger; James M Gavin; Sharmila Adhikari; James E Brownell; Kristine E Burke; David P Cardin; Stephen Critchley; Courtney A Cullis; Amanda Doucette; James J Garnsey; Jeffrey L Gaulin; Rachel E Gershman; Anna R Lublinsky; Alice McDonald; Hirotake Mizutani; Usha Narayanan; Edward J Olhava; Stephane Peluso; Mansoureh Rezaei; Michael D Sintchak; Tina Talreja; Michael P Thomas; Tary Traore; Stepan Vyskocil; Gabriel S Weatherhead; Jie Yu; Julie Zhang; Lawrence R Dick; Christopher F Claiborne; Mark Rolfe; Joseph B Bolen; Steven P Langston
Journal:  Nature       Date:  2009-04-09       Impact factor: 49.962
  9 in total
  2 in total

1.  Drugging SUMOylation for neuroprotection and oncotherapy.

Authors:  Joshua D Bernstock; Daniel G Ye; Yang-Ja Lee; Florian Gessler; Gregory K Friedman; Wei Zheng; John M Hallenbeck
Journal:  Neural Regen Res       Date:  2018-03       Impact factor: 5.135

Review 2.  SUMOylation in Glioblastoma: A Novel Therapeutic Target.

Authors:  Brandon M Fox; Andrew Janssen; Dagoberto Estevez-Ordonez; Florian Gessler; Nunzio Vicario; Gustavo Chagoya; Galal Elsayed; Houman Sotoudeh; William Stetler; Gregory K Friedman; Joshua D Bernstock
Journal:  Int J Mol Sci       Date:  2019-04-15       Impact factor: 5.923
  2 in total

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