BACKGROUND AND AIMS: Laparoscopic sleeve gastrectomy (LSG) might be associated with a new onset or worsening of gastroesophageal reflux disease (GERD). We aim to evaluate the prevalence of post-LSG GERD symptoms and its predictors. METHODS: We included patients who underwent primary LSG at a university hospital from 2009 to 2015. We used the GERD-Health-Related Quality of Life (GERD-HRQL) questionnaire and included questions regarding regurgitation to evaluate symptoms before and after LSG; each item was scored from 1 to 5 based on the symptom severity. RESULTS: A total of 213 patients (mean age, 36.08 ± 10.22 years; 48.36% were men) were included. The mean preoperative body mass index (BMI) was 47.84 kg/m2, mean percent total weight loss was 37.99% (95% CI, 36.64 to 39.34), mean percent excess weight loss was 84.14% (95% CI, 80.91 to 87.36), and the mean percent excess BMI loss was 84.17% (95% CI, 80.94 to 87.41). The mean heartburn score while standing increased (0.71 vs. 1.09, p < 0.01) as well as the score of heartburn requiring a diet change (0.67 vs. 1.16, p < 0.01) post-LSG. The scores for dysphagia, odynophagia, and regurgitation increased. New-onset heartburn was reported in 47.06% of our cohort. Those with high preoperative BMIs were less likely to develop new-onset or worsening symptoms of GERD (odds ratio [OR], 0.97; 95% confidence interval [CI], 0.95-0.99). More severe heartburn symptoms while standing were associated with higher risks of developing or worsening GERD symptoms (OR, 1.22; 95% CI, 1.01-1.47). None of the other variables could predict the development or worsening of the GERD symptoms. CONCLUSION: Symptoms of heartburn and regurgitation are common after LSG; however, none of the variables preoperatively could strongly predict patients who would develop new onset or experience worsening of symptoms postoperatively.
BACKGROUND AND AIMS: Laparoscopic sleeve gastrectomy (LSG) might be associated with a new onset or worsening of gastroesophageal reflux disease (GERD). We aim to evaluate the prevalence of post-LSG GERD symptoms and its predictors. METHODS: We included patients who underwent primary LSG at a university hospital from 2009 to 2015. We used the GERD-Health-Related Quality of Life (GERD-HRQL) questionnaire and included questions regarding regurgitation to evaluate symptoms before and after LSG; each item was scored from 1 to 5 based on the symptom severity. RESULTS: A total of 213 patients (mean age, 36.08 ± 10.22 years; 48.36% were men) were included. The mean preoperative body mass index (BMI) was 47.84 kg/m2, mean percent total weight loss was 37.99% (95% CI, 36.64 to 39.34), mean percent excess weight loss was 84.14% (95% CI, 80.91 to 87.36), and the mean percent excess BMI loss was 84.17% (95% CI, 80.94 to 87.41). The mean heartburn score while standing increased (0.71 vs. 1.09, p < 0.01) as well as the score of heartburn requiring a diet change (0.67 vs. 1.16, p < 0.01) post-LSG. The scores for dysphagia, odynophagia, and regurgitation increased. New-onset heartburn was reported in 47.06% of our cohort. Those with high preoperative BMIs were less likely to develop new-onset or worsening symptoms of GERD (odds ratio [OR], 0.97; 95% confidence interval [CI], 0.95-0.99). More severe heartburn symptoms while standing were associated with higher risks of developing or worsening GERD symptoms (OR, 1.22; 95% CI, 1.01-1.47). None of the other variables could predict the development or worsening of the GERD symptoms. CONCLUSION: Symptoms of heartburn and regurgitation are common after LSG; however, none of the variables preoperatively could strongly predict patients who would develop new onset or experience worsening of symptoms postoperatively.
Authors: Majid A Almadi; Maitha A Almousa; Amani F Althwainy; Afnan M Altamimi; Hala O Alamoudi; Hiba S Alshamrani; Othman R Alharbi; Nahla A Azzam; Nazia Sadaf; Abdulrahman M Aljebreen Journal: Saudi J Gastroenterol Date: 2014 Jul-Aug Impact factor: 2.485
Authors: Gianmattia Del Genio; Salvatore Tolone; Paolo Limongelli; Luigi Brusciano; Antonio D'Alessandro; Giovanni Docimo; Gianluca Rossetti; Gianfranco Silecchia; Antonio Iannelli; Alberto del Genio; Federica del Genio; Ludovico Docimo Journal: Obes Surg Date: 2014-01 Impact factor: 4.129
Authors: Lars Fischer; Anna-Laura Wekerle; Thomas Bruckner; Inga Wegener; Markus K Diener; Moritz V Frankenberg; Daniel Gärtner; Michael R Schön; Matthias C Raggi; Emre Tanay; Rainer Brydniak; Norbert Runkel; Corinna Attenberger; Min-Seop Son; Andreas Türler; Rudolf Weiner; Markus W Büchler; Beat P Müller-Stich Journal: BMC Surg Date: 2015-07-18 Impact factor: 2.102
Authors: Ziad A Memish; Charbel El Bcheraoui; Marwa Tuffaha; Margaret Robinson; Farah Daoud; Sara Jaber; Sarah Mikhitarian; Mohammed Al Saeedi; Mohammad A AlMazroa; Ali H Mokdad; Abdullah A Al Rabeeah Journal: Prev Chronic Dis Date: 2014-10-09 Impact factor: 2.830
Authors: Shailendra Singh; Diogo Turiani Hourneaux de Moura; Ahmad Khan; Mohammad Bilal; Michele B Ryan; Christopher C Thompson Journal: Surg Obes Relat Dis Date: 2019-12-10 Impact factor: 4.734
Authors: Abdullah Dalboh; Dafer M Al-Shehri; Walid M Abd El Maksoud; Khaled S Abbas; Abdulrahman J Alqahtani; Adnan Q Al-Malki; Khalid A Al-Shahrani Journal: Obes Surg Date: 2021-03-29 Impact factor: 4.129
Authors: Ayman El Nakeeb; Hassan Aldossary; Ahmed Zaid; Mohamed El Sorogy; Mohamad Elrefai; Mohamed Attia; Alaa Mostafa Sewefy; Taha Kayed; Mubarak Al-Shari Aldawsari; Hathal Mashan Al Dossari; Mohammed M Mohammed Journal: Obes Surg Date: 2022-09-10 Impact factor: 3.479
Authors: Radu Neagoe; Mircea Muresan; Daniel Timofte; Ruxandra Darie; Ion Razvan; Septimiu Voidazan; Simona Muresan; Daniela Sala Journal: Wideochir Inne Tech Maloinwazyjne Date: 2019-04-08 Impact factor: 1.195
Authors: Victoria Salem; Noara AlHusseini; Habeeb Ibrahim Abdul Razack; Anastasia Naoum; Omar T Sims; Saleh A Alqahtani Journal: Obes Rev Date: 2022-03-26 Impact factor: 10.867